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Proteintech
ING2 Monoclonal Antibody (2C3A7), CoraLite® Plus 488
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Product Details
CL488-66512
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2C3A7
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MLGQQQQQLY SSAALLTGER SRLLTCYVQD YLECVESLPH DMQRNVSVLR ELDNKYQETL KEIDDVYEKY KKEDDLNQKK RLQQLLQRAL INSQELGDEK IQIVTQMLEL VENRARQMEL HSQCFQDPAE SERASDKAKM DSSQPERSSR RPRRQRTSES RDLCHMANGI EDCDDQPPKE KKSKSAKKKK RSKAKQEREA SPVEFAIDPN EPTYCLCNQV SYGEMIGCDN EQCPIEWFHF SCVSLTYKPK GKWYCPKCRG DNEKTMDKST EKTKKDRRSR
Target Information
This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ING1Lp; Inhibitor of growth 1-like protein; Inhibitor of growth protein 2; p32; p33ING2; unnamed protein product
Gene Aliases: 2810011M06Rik; ING1L; ING2; Ing2b; P33ING2
UniProt ID: (Human) Q9H160, (Mouse) Q9ESK4
Entrez Gene ID: (Human) 3622, (Mouse) 69260, (Rat) 290744
DNA binding
chromatin binding
protein binding
zinc ion binding
histone deacetylase regulator activity
phosphatidylinositol binding
macromolecular complex binding
metal ion binding
histone H3K4me3 reader activity
histone reader activity
protein complex binding
methylated histone binding
molecular_function
chromatin/chromatin-binding, or -regulatory protein
negative regulation of transcription from RNA polymerase II promoter
chromatin organization
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
male meiosis I
signal transduction
spermatogenesis
spermatid development
sperm motility
negative regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of gene expression, epigenetic
positive regulation of transcription, DNA-templated
male germ-line stem cell asymmetric division
seminiferous tubule development
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of stem cell population maintenance
positive regulation of stem cell population maintenance
regulation of cellular senescence
negative regulation of apoptotic signaling pathway
transcription, DNA-templated
negative regulation of cell proliferation
chromatin modification
regulation of growth
positive regulation of apoptotic process
biological_process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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