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Proteintech

CTBP1 Monoclonal Antibody (1C4B2), CoraLite® Plus 488

View all (26) CtBP1 antibodies

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Product Details

CL488-66995

Applications
Tested Dilution
Publications

Immunocytochemistry (ICC/IF)

1:50-1:500
-

Flow Cytometry (Flow)

Assay-dependent
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1C4B2

Immunogen

Full length CtBP1 protein.

Conjugate

CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488

Excitation/Emission Max

493/522 nm

Form

Liquid

Concentration

2 mg/mL

Amount

200 µg

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 0.5% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C, store in dark

Shipping conditions

Wet ice

Target Information

This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 50 kDa BFA-dependent ADP-ribosylation substrate; 50-kDa BFA-induced ADP-ribosylated substrate; BARS-50; brefeldin A-ADP-riboslyated substrate; brefeldin A-ribosylated substrate; C-terminal-binding protein 1; C-terminal-binding protein 3; C-terminus binding protein 3/brefeldin A (BFA) adenosine diphosphate-ribosylated substrate; CtBP1; CtBP3; MGC104684; transcriptional repressor

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Gene Aliases: 50-kDaBFA-inducedADP-ribosylatedsubstrate; BARS; BARS-50; CTBP; CTBP1; CtBP1-L; CtBP1-S; Ctbp3; CtBP3/BARS; D4S115h; D5H4S115; D5H4S115E; HADDTS

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UniProt ID: (Human) Q13363, (Rat) Q9Z2F5, (Mouse) O88712

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Entrez Gene ID: (Human) 1487, (Rat) 29382, (Mouse) 13016

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Function(s)
transcription cofactor binding transcription corepressor binding chromatin binding transcription coactivator activity transcription corepressor activity protein binding oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor protein domain specific binding identical protein binding NAD binding RNA polymerase II sequence-specific DNA binding transcription factor binding lncRNA binding DNA-binding transcription factor binding RNA polymerase II transcription corepressor activity transcription factor activity, sequence-specific DNA binding transcription factor binding transferase activity, transferring acyl groups protein homodimerization activity repressing transcription factor binding C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity aldo-keto reductase (NADP) activity isocitrate dehydrogenase activity mevaldate reductase activity gluconate dehydrogenase activity steroid dehydrogenase activity epoxide dehydrogenase activity 5-exo-hydroxycamphor dehydrogenase activity 2-hydroxytetrahydrofuran dehydrogenase activity acetoin dehydrogenase activity phenylcoumaran benzylic ether reductase activity D-xylose:NADP reductase activity L-arabinose:NADP reductase activity D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor steroid dehydrogenase activity, acting on the CH-CH group of donors (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity 3-hydroxymenthone dehydrogenase activity very long-chain-3-hydroxyacyl-CoA dehydrogenase activity dihydrotestosterone 17-beta-dehydrogenase activity (R)-2-hydroxyisocaproate dehydrogenase activity L-arabinose 1-dehydrogenase (NADP+) activity L-xylulose reductase (NAD+) activity 3-ketoglucose-reductase activity (R)-2-hydroxyglutarate dehydrogenase activity D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity transcription cofactor
Process(es)
negative regulation of transcription from RNA polymerase II promoter regulation of transcription from RNA polymerase II promoter protein phosphorylation Notch signaling pathway negative regulation of cell proliferation viral genome replication cell differentiation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated synaptic vesicle endocytosis white fat cell differentiation regulation of cell cycle synaptic vesicle clustering transcription, DNA-templated positive regulation of histone deacetylation negative regulation of histone acetylation oxidation-reduction process membrane fusion negative regulation of histone H4 acetylation negative regulation of transcription from RNA polymerase II promoter by histone modification regulation of transcription, DNA-templated transcription from RNA polymerase II promoter metabolic process
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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