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Proteintech
GNAI2 Monoclonal Antibody (3F6H5), CoraLite® Plus 488
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Product Details
CL488-67007
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3F6H5
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein G
Storage buffer
PBS with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MGCTVSAEDK AAAERSKMID KNLREDGEKA AREVKLLLLG AGESGKSTIV KQMKIIHEDG YSEEECRQYR AVVYSNTIQS IMAIVKAMGN LQIDFADPSR ADDARQLFAL SCTAEEQGVL PDDLSGVIRR LWADHGVQAC FGRSREYQLN DSAAYYLNDL ERIAQSDYIP TQQDVLRTRV KTTGIVETHF TFKDLHFKMF DVGGQRSERK KWIHCFEGVT AIIFCVALSA YDLVLAEDEE MNRMHESMKL FDSICNNKWF TDTSIILFLN KKDLFEEKIT HSPLTICFPE YTGANKYDEA ASYIQSKFED LNKRKDTKEI YTHFTCATDT KNVQFVFDAV TDVIIKNNLK DCGLF
Target Information
The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins). The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only two are known so far.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adenylate cyclase-inhibiting G alpha protein; BR; CD49B; G alpha inhibitory type 2 (a); G alpha inhibitory type 2 (b); G protein; GNAI2; GPIa; GTP-binding protein (G-alpha-i2); GTP-binding regulatory protein Gi alpha-2 chain; guanine nucleotide binding protein (G protein), alpha inhibiting 2; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2; guanine nucleotide binding protein, alpha inhibiting 2; Guanine nucleotide-binding protein G(i) subunit alpha-2; guanine nucleotide-binding protein G(i), alpha-2 subunit; guanine nucleotide-binding regulatory protein alpha-inhibitory subunit; heterotrimeric guanine nucleotide-binding protein 1C; sGi2; unnamed protein product; VLA-2; VLAA2
Gene Aliases: C76432; Galphai2; Gia; GIP; Gnai-2; GNAI2; GNAI2B; H_LUCA15.1; H_LUCA16.1; HG1C
UniProt ID: (Human) P04899, (Rat) P04897, (Mouse) P08752
Entrez Gene ID: (Human) 2771, (Rat) 81664, (Mouse) 14678
adenosine receptor signaling pathway
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase activity
G-protein coupled acetylcholine receptor signaling pathway
gamma-aminobutyric acid signaling pathway
response to nutrient
cell proliferation
positive regulation of cell proliferation
positive regulation of cell migration
positive regulation of superoxide anion generation
positive regulation of urine volume
negative regulation of calcium ion-dependent exocytosis
modulation of synaptic transmission
negative regulation of synaptic transmission
cell division
regulation of calcium ion transport
positive regulation of ERK1 and ERK2 cascade
negative regulation of adrenergic receptor signaling pathway
positive regulation of vascular smooth muscle cell proliferation
positive regulation of neural precursor cell proliferation
negative regulation of apoptotic signaling pathway
activation of MAPKK activity
G-protein coupled glutamate receptor signaling pathway
regulation of heart contraction
metabolic process
intracellular signal transduction
cell cycle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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