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Frizzled 9 Monoclonal Antibody (1G9G4), CoraLite® Plus 488
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FIGURE: 1 / 1
Frizzled 9 Antibody (CL488-67023) in Flow
1X10^6 HeLa cells were intracellularly stained with 0.4 µg CoraLite® Plus 488 Anti-Human Frizzled 9 (CL488-67023, Clone:1G9G4) (red), or 0.4 µg Control Antibody. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
Product Details
CL488-67023
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1G9G4
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein G
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: LEIGRFDPER GRGAAPCQAV EIPMCRGIGY NLTRMPNLLG HTSQGEAAAE LAEFAPLVQY GCHSHLRFFL CSLYAPMCTD QVSTPIPACR PMCEQARLRC APIMEQFNFG WPDSLDCARL PTRNDPHALC MEAPENATAG PAEPHKGLGM LPVAPRPARP PGDLGPGAGG SGTCENREKF QYVEKSRSCA PRCGPGVEVF WSRRDKDFAL VWMAVWSALC FFSTA
Target Information
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD349; CD349 antigen; Frizzled 3; frizzled 9, seven transmembrane spanning receptor; frizzled family receptor 9; frizzled homolog 9; Frizzled-3; Frizzled-9; Frizzled3; Frizzled9; Fz-9; FzE6; hFz9; similar to Drosophila frizzled
Gene Aliases: CD349; FZD3; FZD9
UniProt ID: (Human) O00144
Entrez Gene ID: (Human) 8326
ossification
release of cytochrome c from mitochondria
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
nervous system development
neuroblast proliferation
learning or memory
Wnt signaling pathway
B cell differentiation
positive regulation of bone mineralization
non-canonical Wnt signaling pathway
positive regulation of apoptotic process
negative regulation of neuron apoptotic process
regulation of cytosolic calcium ion concentration
regulation of cell cycle
negative regulation of mitochondrial depolarization
canonical Wnt signaling pathway
negative regulation of necroptotic process
positive regulation of canonical Wnt signaling pathway
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
regulation of skeletal muscle acetylcholine-gated channel clustering
negative regulation of skeletal muscle acetylcholine-gated channel clustering
bone regeneration
positive regulation of neural precursor cell proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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