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Proteintech
CES1 Monoclonal Antibody (1C11C1), CoraLite® Plus 488
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Product Details
CL488-67079
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1C11C1
Immunogen
Recombinant Protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
2 mg/mL
Amount
200 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Target Information
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACAT; acyl coenzyme A:cholesterol acyltransferase; Acyl-coenzyme A:cholesterol acyltransferase; Brain carboxylesterase hBr1; Carboxylesterase 1; carboxylesterase 1 (monocyte/macrophage serine esterase 1); carboxylesterase 2 (liver); carboxylesterase; ACAT; CE-1; CEH; Cholesteryl ester hydrolase; Cocaine carboxylesterase; Egasyn; ER-resident carboxylesterase; HMSE; human monocyte/macrophage serine esterase 1; Liver carboxylesterase 1; Methylumbelliferyl-acetate deacetylase 1; MGC117365; Monocyte/macrophage serine esterase; REH; Retinyl ester hydrolase; Serine esterase 1; TGH; triacylglycero; Triacylglycerol hydrolase; unnamed protein product
Gene Aliases: ACAT; CE-1; CEH; CES1; CES2; hCE-1; HMSE; HMSE1; PCE-1; REH; SES1; TGH
UniProt ID: (Human) P23141
Entrez Gene ID: (Human) 1066
lipid metabolic process
cholesterol biosynthetic process
cholesterol metabolic process
response to toxic substance
positive regulation of cholesterol efflux
negative regulation of cholesterol storage
lipid catabolic process
epithelial cell differentiation
cholesterol homeostasis
reverse cholesterol transport
medium-chain fatty acid metabolic process
regulation of bile acid biosynthetic process
cellular response to cholesterol
cellular response to low-density lipoprotein particle stimulus
cholesterol ester hydrolysis involved in cholesterol transport
positive regulation of cholesterol metabolic process
regulation of bile acid secretion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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