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Proteintech
TPM4 Monoclonal Antibody (2E12D12), CoraLite® Plus 488
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Product Details
CL488-67244
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2E12D12
Immunogen
TPM4 fusion protein Ag6947
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MAGLNSLEA VKRKIQALQQ QADEAEDRAQ GLQRELDGER ERREKAEGDV AALNRRIQLV EEELDRAQER LATALQKLEE AEKAADESER GMKVIENRAM KDEEKMEIQE MQLKEAKHIA EEADRKYEEV ARKLVILEGE LERAEERAEV SELKCGDLEE ELKNVTNNLK SLEAASEKYS EKEDKYEEEI KLLSDKLKEA ETRAEFAERT VAKLEKTIDD LEEKLAQAKE ENVGLHQTLD QTLNELNCI
Target Information
TPM4 (tropomyosin 4) is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM4 plays a central role in association with the troponin complex in the calcium dependent regulations of vertebrate striated muscle contraction. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cytoskeletal tropomyosin isoform; epididymis secretory protein Li 108; TM-4; TM30p1; tropomycin 4; tropomyosin; Tropomyosin alpha-4 chain; Tropomyosin-4; unnamed protein product
Gene Aliases: 2610528G24Rik; BDPLT25; HEL-S-108; TPM4; Tpm4.2; Tpm4.2cy
UniProt ID: (Pig) P67937, (Human) P67936, (Rat) P09495, (Mouse) Q6IRU2
Entrez Gene ID: (Pig) 397608, (Human) 7171, (Rat) 24852, (Mouse) 326618
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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