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Proteintech
UGDH Monoclonal Antibody (1E2E1), CoraLite® Plus 488
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Product Details
CL488-67360
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1E2E1
Immunogen
UGDH fusion protein Ag29747
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MFEIKKICC IGAGYVGGPT CSVIAHMCPE IRVTVVDVNE SRINAWNSPT LPIYEPGLKE VVESCRGKNL FFSTNIDDAI KEADLVFISV NTPTKTYGMG KGRAADLKYI EACARRIVQN SNGYKIVTEK STVPVRAAES IRRIFDANTK PNLNLQVLSN PEFLAEGTAI KDLKNPDRVL IGGDETPEGQ RAVQALCAVY EHWVPREKIL TTNTWSSELS KLAANAFLAQ RISSINSISA LCEATGADVE EVATAIGMDQ RIGNKFLKAS VGFGGSCFQK DVLNLVYLCE ALNLPEVARY WQ
Target Information
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: UDP UGD; UDP-Glc dehydrogenase; UDP-GlcDH; UDP-glucose 6-dehydrogenase; UDP-glucose dehydrogeanse; UDP-glucose dehydrogenase; UDPGDH; UDPGDH; NAD+-linked oxidoreductase; unnamed protein product; uridine diphospho-glucose dehydrogenase
Gene Aliases: DEE84; EIEE84; GDH; UDP-GlcDH; UDPGDH; UGD; UGDH
UniProt ID: (Human) O60701, (Rat) O70199, (Mouse) O70475
Entrez Gene ID: (Pig) 100627727, (Human) 7358, (Rat) 83472, (Mouse) 22235
gastrulation with mouth forming second
glycosaminoglycan biosynthetic process
UDP-glucuronate biosynthetic process
heparan sulfate proteoglycan biosynthetic process
protein hexamerization
neuron development
chondroitin sulfate proteoglycan biosynthetic process
oxidation-reduction process
metabolic process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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