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Proteintech
ACC Monoclonal Antibody (1A11G10), CoraLite® Plus 488
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Product Details
CL488-67373
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1A11G10
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: LLEDLVKKKI HNANPELTDG QIQAMLRRWF VEVEGTVKAY VWDNNKDLAE WLEKQLTEED GVHSVIEENI KCISRDYVLK QIRSLVQANP EVAMDSIIHM TQHISPTQRA EVIRILSTMD SPST
Target Information
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acaca; ACC-alpha; ACC1; Acetyl-CoA carboxylase 1; Acetyl-CoA carboxylase 265; Acetyl-Coenzyme A carboxylase alpha; EC 6.3.4.14; EC 6.4.1.2; unnamed protein product
Gene Aliases: A530025K05Rik; ACAC; Acac1; ACACA; ACACAD; ACACalpha; ACC; ACC1; ACCA; ACCalpha; Gm738; hACC1
UniProt ID: (Human) Q13085, (Mouse) Q5SWU9, (Rat) P11497
Entrez Gene ID: (Human) 31, (Mouse) 107476, (Rat) 60581
tissue homeostasis
acetyl-CoA metabolic process
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
metabolic process
response to organic cyclic compound
multicellular organismal protein metabolic process
protein homotetramerization
lipid homeostasis
cellular response to prostaglandin E stimulus
acyl-CoA metabolic process
lipid biosynthetic process
fatty-acyl-CoA biosynthetic process
malonyl-CoA biosynthetic process
response to drug
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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