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Proteintech
PI3 Kinase p85 Beta Monoclonal Antibody (2B3B6), CoraLite® Plus 488
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Product Details
CL488-67644
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
2B3B6
Immunogen
PI3 Kinase p85 Beta fusion protein Ag14369
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: YRHESLAQY NAKLDTRLLY PVSKYQQDQI VKEDSVEAVG AQLKVYHQQY QDKSREYDQL YEEYTRTSQE LQMKRTAIEA FNETIKIFEE QGQTQEKCSK EYLERFRREG NEKEMQRILL NSERLKSRIA EIHESRTKLE QQLRAQASDN REIDKRMNSL KPDLMQLRKI RDQYLVWLTQ KGARQKKINE WLGIKNETED QYALMEDEDD LPHHEERTWY VGKINRTQAE EMLSGKRDGT FLIRESSQRG CYACSVVVDG DTKHCVIYRT ATGFGFAEPY NLYGSLKELV LHYQHASLVQ HNDALTVTLA HPVRAPGPGP PPAAR
Target Information
Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; phosphatidylinositol 3-kinase regulartory subunit polypeptide 2; Phosphatidylinositol 3-kinase regulatory subunit beta; phosphatidylinositol 3-kinase, regulartory subunit, polypeptide 2; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta); phosphoinositide-3-kinase regulatory subunit beta; phosphoinositide-3-kinase, regulatory subunit 2 (beta); PI3-kinase p85 subunit beta; PI3-kinase regulatory subunit beta; PI3-kinase subunit p85-beta; PI3K; PI3K regulatory subunit beta; ptdIns-3-kinase p85-beta; ptdIns-3-kinase regulatory subunit beta; ptdIns-3-kinase regulatory subunit p85-beta
Gene Aliases: MPPH; MPPH1; p85; p85-BETA; P85B; p85beta; PIK3R2
UniProt ID: (Human) O00459, (Mouse) O08908
Entrez Gene ID: (Human) 5296, (Mouse) 18709, (Rat) 29741
phosphotyrosine binding
GTPase activator activity
protein binding
protein phosphatase binding
receptor tyrosine kinase binding
phosphatidylinositol 3-kinase regulatory subunit binding
1-phosphatidylinositol-3-kinase regulator activity
protein heterodimerization activity
transcription factor binding
1-phosphatidylinositol-3-kinase activity
phosphatidylinositol 3-kinase regulator activity
kinase modulator
cellular glucose homeostasis
immune response
signal transduction
insulin receptor signaling pathway
regulation of autophagy
protein transport
B cell differentiation
T cell differentiation
regulation of actin filament polymerization
cellular response to insulin stimulus
response to endoplasmic reticulum stress
positive regulation of protein import into nucleus
negative regulation of MAPK cascade
protein kinase B signaling
positive regulation of cell adhesion
positive regulation of transcription from RNA polymerase II promoter
regulation of stress fiber assembly
regulation of protein localization to plasma membrane
transport
phosphatidylinositol 3-kinase signaling
regulation of phosphorylation
positive regulation of transcription factor import into nucleus
regulation of phosphatidylinositol 3-kinase activity
phosphatidylinositol phosphorylation
regulation of establishment of protein localization to plasma membrane
phosphorylation
phosphatidylinositol-3-phosphate biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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