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Proteintech
TNC/Tenascin-C Monoclonal Antibody (1F7G8), CoraLite® Plus 488
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Product Details
CL488-67710
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1F7G8
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein G
Storage buffer
PBS with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: YALTDLEPAT EYTLRIFAEK GPQKSSTITA KFTTDLDSPR DLTATEVQSE TALLTWRPPR ASVTGYLLVY ESVDGTVKEV IVGPDTTSYS LADLSPSTHY TAKIQALNGP LRSNMIQTIF TTIGLLYPFP KDCSQAMLNG DTTSGLYTIY LNGDKAEALE VFCDMTSDGG GWIVFLRRKN GRENFYQNWK AYAAGFGDRR EEFWLGLDNL NKITAQGQYE LRVDLRDHGE TAFAVYDKFS VGDAKTRYKL KVEGYSGTAG DSMAYHNGRS FSTFDKDTDS AITNCALSYK GAFWYRNCHR VNLMGRYGDN NHSQGVNWFH WKGHEHSIQF AEMKLRPSNF RNLEGRRKRA
Target Information
Tenascin is a high molecular weight, multifunctional, extracellular matrix glycoprotein expressed in association with mesenchymal-epithelial interactions during development and in the neovasculature and stroma of undifferentiated tumors (Erickson and Bourdon 1989). It has been described under a variety of names: cytotactin, hexabrachion protein, J1, myotendinous antigen (MI) and glioma mesenchymal extracellular matrix (GMEM). The tenascin molecule is a disulfide-linked hexamer. The expression of tenascin is associated with development and growth, both normal and pathological, whereas the distribution in normal adult tissue is restricted.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytotactin; deafness, autosomal dominant 56; ECM glycoprotein; TNC-14/AD1/16; Glioma-associated-extracellular matrix antigen; GMEM; GP 150-225; Hexabrachion; hexabrachion (tenascin); JI; MGC144208; MGC144209; MGC167029; Myotendinous antigen; Neuronectin; Tenascin; Tenascin-C; tenascin-C additional domain 1; tenascin-C FN type III repeat domain; tenascin-C AD1; TN; TN-C; tnc; unnamed protein product
Gene Aliases: 150-225; AI528729; C130033P17Rik; cytotactin; DFNA56; GMEM; GP; HXB; JI; Ten; tenascin-C; TN; TN-C; TNC
UniProt ID: (Human) P24821, (Mouse) Q80YX1
Entrez Gene ID: (Human) 3371, (Rat) 116640, (Mouse) 21923
regulation of cell growth
osteoblast differentiation
morphogenesis of an epithelium
cell adhesion
negative regulation of cell adhesion
neuromuscular junction development
positive regulation of cell proliferation
response to wounding
response to mechanical stimulus
positive regulation of gene expression
peripheral nervous system axon regeneration
regulation of cell adhesion
regulation of cell migration
neuron projection development
odontogenesis of dentin-containing tooth
response to ethanol
regulation of inflammatory response
bud outgrowth involved in lung branching
mesenchymal-epithelial cell signaling involved in prostate gland development
prostate gland epithelium morphogenesis
cellular response to retinoic acid
cellular response to vitamin D
response to fibroblast growth factor
cellular response to prostaglandin D stimulus
wound healing
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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