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Proteintech
ELAVL4 Monoclonal Antibody (1B1F5), CoraLite® Plus 488
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Product Details
CL488-67835
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1B1F5
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MVMIISTMEP QVSNGPTSNT SNGPSSNNRN CPSPMQTGAT TDDSKTNLIV NYLPQNMTQE EFRSLFGSIG EIESCKLVRD KITGQSLGYG FVNYIDPKDA EKAINTLNGL RLQTKTIKVS YARPSSASIR DANLYVSGLP KTMTQKELEQ LFSQYGRIIT SRILVGQVTG VSRGVGFIRF DKRIEAEEAI KGLNGQKPSG ATEPITVKFA NNPSQKSSQA LLSQLYQSPN RRYPGPLHHQ AQRFRLDNLL NMAYGVKRFS PITIDGMTSL VGMNIPGHTG TGWCIFVYNL SPDSDESVLW QLFGPFGAVN NVKVIRDFNT NKCKGFGFVT MTNYDEAAMA ITSLNGYRLG DRVLQVSFKT NKAHKS
Target Information
HuD, otherwise known as ELAV-like protein 4 or PNEM, is a protein that in humans is encoded by the ELAVL4 gene. This human gene is located at 1p34 by in situ hybridization. The HuD/ELAVL4 protein is an RNA-binding protein. ELAVL4 has specificity for 3-prime uridylate-rich untranslated regions of growth factor mRNAs. HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs. As a result of this interaction the, half-life of the transcript is increased. Additionally, HuD is important in neurons during brain development and plasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D); ELAV like neuron-specific RNA binding protein 4; ELAV-like protein 4; Hu antigen D; HU-antigen D; HuD; paraneoplastic encephalomyelitis antigen; Paraneoplastic encephalomyelitis antigen HuD; RNA-binding protein HUD3; unnamed protein product
Gene Aliases: Elav; ELAVL4; HUD; PNEM; r-HuD; RGD1561943
UniProt ID: (Human) P26378, (Mouse) Q61701, (Rat) O09032
Entrez Gene ID: (Rabbit) 100359216, (Human) 1996, (Mouse) 15572, (Rat) 432358
RNA processing
mRNA processing
learning
locomotory behavior
RNA splicing
cerebral cortex neuron differentiation
dendrite morphogenesis
3'-UTR-mediated mRNA stabilization
positive regulation of 3'-UTR-mediated mRNA stabilization
neuron differentiation
regulation of mRNA stability
positive regulation of dendrite development
nervous system development
aging
associative learning
regeneration
response to endoplasmic reticulum stress
response to cocaine
cellular response to nerve growth factor stimulus
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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