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Proteintech
HSPB11 Monoclonal Antibody (2D11B3), CoraLite® Plus 488
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FIGURE: 1 / 1
HSPB11 Antibody (CL488-68059) in Flow
1X10^6 HeLa cells were intracellularly stained with 0.4 µg CoraLite® Plus 488 Anti-Human HSPB11 (CL488-68059, Clone:2D11B3) (red), or 0.4 µg Mouse IgG2a Isotype Control (CL488-66360-2, Clone: K11A1B2A2) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
Product Details
CL488-68059
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
2D11B3
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MRKIDLCLSS EGSEVILATS SDEKHPPENI IDGNPETFWT TTGMFPQEFI ICFHKHVRIE RLVIQSYFVQ TLKIEKSTSK EPVDFEQWIE KDLVHTEGQL QNEEIVAHDG SATYLRFIIV SAFDHFASVH SVSAEGTVVS NLSS
Target Information
HSPB11 (Heat shock protein beta-11), also known as IFT25, was originally identified as a small heat shock protein. Recently it has been identified as a component of IFT complex B. It has been demonstrated that IFT25 is not required for ciliary assembly but is required for proper Hedgehog signaling, which in mammals occurs within cilia. Cilia lacking IFT25 have defects in the signal-dependent transport of multiple Hedgehog components and fail to activate the pathway upon stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Heat shock protein; Heat shock protein beta-11; heat shock protein family B (small), member 11; Heat shock protein family B member 11; HSP; Hspb11; intraflagellar transport 25 homolog; Intraflagellar transport protein 25 homolog; Placental protein 25; PP25
Gene Aliases: C1orf41; HSPB11; HSPC034; HSPCO34; IFT25; PP25
UniProt ID: (Human) Q9Y547
Entrez Gene ID: (Human) 51668
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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