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Proteintech
MYDGF/C19orf10 Monoclonal Antibody (1H8F4), CoraLite® Plus 488
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Product Details
CL488-68131
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1H8F4
Immunogen
MYDGF/C19orf10 fusion protein Ag13438
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MAAPSGGWN GVGASLWAAL LLGAVALRPA EAVSEPTTVA FDVRPGGVVH SFSHNVGPGD KYTCMFTYAS QGGTNEQWQM SLGTSEDHQH FTCTIWRPQG KSYLYFTQFK AEVRGAEIEY AMAYSKAAFE RESDVPLKTE EFEVTKTAVA HRPGAFKAEL SKLVIVAKAS RTEL
Target Information
The interleukins are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. IL-25 (also called SF20/IL-25) is a secreted bone marrow stroma-derived growth factor cytokine that is derived from Th2 T-cells. IL-25 belongs to the IL-17 cytokine family and is capable of amplifying allergic type inflammatory responses by its actions on other cell types. IL-25 binds to mouse thymic shared antigen-1 and supports lymphoid cell proliferation. Infusion of mice with IL-25 induces IL-4, IL-5, and IL-13 gene expression. IL-25 induced mice also develop epithelial cell hyperplasia, increased mucus secretion, and airway hyperreactivity, suggesting that IL-25 may be an important mediator of allergic disease via production of IL-4, IL-5, IL-13 and eotaxin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CS010; IL 25; IL 27; interleukin 27 working designation; interleukin-25; Interleukin25; MYDGF; Myeloid-derived growth factor; R33729 1; R337291; similar to lymphocyte antigen 6 complex, locus E ligand; stromal cell-derived growth factor SF20; UPF0556 protein C19orf10; UPF0556 protein C19orf10 homolog
Gene Aliases: C19orf10; D17Wsu104e; EUROIMAGE1875335; IL25; IL27; IL27w; Ly6elg; MYDGF; R33729_1; SF20
UniProt ID: (Human) Q969H8, (Mouse) Q9CPT4
Entrez Gene ID: (Rat) 501282, (Human) 56005, (Mouse) 28106
positive regulation of endothelial cell proliferation
positive regulation of angiogenesis
angiogenesis
positive regulation of protein phosphorylation
apoptotic process
negative regulation of apoptotic process
positive regulation of MAPK cascade
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein kinase B signaling
positive regulation of phosphatidylinositol 3-kinase signaling
cellular response to brefeldin A
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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