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Proteintech
LANCL1 Monoclonal Antibody (2H6E8), CoraLite® Plus 488
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Product Details
CL488-68160
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2H6E8
Immunogen
LANCL1 fusion protein Ag32665
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: TKRSITFLC GDAGPLAVAA VLYHKMNNEK QAEDCITRLI HLNKIDPHAP NEMLYGRIGY IYALLFVNKN FGVEKIPQSH IQQICETILT SGENLARKRN FTAKSPLMYE WYQEYYVGAA HGLAGIYYYL MQPSLQVSQG KLHSLVKPSV DYVCQLKFPS GNYPPCIGDN RDLLVHWCHG APGVIYMLIQ AYKVFREEKY LCDAYQCADV IWQYGLLKKG YGLCHGSAGN AYAFLTLYNL TQDMKYLYRA CKFAEWCLEY GEHGCRTPDT PFSLFEGMAG TIYFLADLLV PTKARFPAFE L
Target Information
NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 40 kDa erythrocyte membrane protein; G protein-coupled receptor 69; G protein-coupled receptor 69A; Glutathione S-transferase LANCL1; LanC (bacterial lantibiotic synthetase component C)-like 1; LanC (bacterial lantibiotic synthetase component); LanC lantibiotic synthetase component C-like 1; LanC-like 1; LanC-like 1(bacterial); LanC-like protein 1; p40
Gene Aliases: AW124738; Gpr69; GPR69A; LANCL1; p40
UniProt ID: (Human) O43813, (Rat) Q9QX69, (Mouse) O89112
Entrez Gene ID: (Pig) 100153701, (Human) 10314, (Rat) 114515, (Mouse) 14768
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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