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Proteintech
DDX4, VASA Monoclonal Antibody (1F12C3), CoraLite® Plus 488
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Product Details
CL48867147100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1F12C3
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
Target Information
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a homolog of VASA proteins in Drosophila and several other species. The gene is specifically expressed in the germ cell lineage in both sexes and functions in germ cell development. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent RNA helicase DDX4; D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 4; DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 4; DEAD box polypeptide 4; DEAD box protein 4; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4; MGC111074; Mvh; mvh / m'vasa; Probable ATP-dependent RNA helicase DDX4; unnamed protein product; VASA; Vasa homolog
Gene Aliases: AV206478; DDX4; Mvh; VASA
UniProt ID: (Human) Q9NQI0, (Mouse) Q61496
Entrez Gene ID: (Human) 54514, (Mouse) 13206
male meiosis
male meiosis I
gamete generation
germ cell development
spermatogenesis
cell differentiation
sperm motility
gene silencing by RNA
piRNA metabolic process
meiotic cell cycle
transposable element silencing by piRNA-mediated heterochromatin formation
transposable element silencing by piRNA-mediated DNA methylation
multicellular organism development
RNA secondary structure unwinding
regulation of protein localization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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