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Proteintech
NQO1 Monoclonal Antibody (1E5G7), CoraLite® Plus 488
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
CL48867240100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1E5G7
Conjugate
CoraLite® Plus 488
CoraLite® Plus 488
CoraLite® Plus 488
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
Target Information
NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Altered expression of the protein has been seen in many tumors and is also associated with Alzheimer's disease (AD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: azoreductase; Diaphorase (NADH/NADPH); diaphorase (NADH/NADPH) (cytochrome b-5 reductase); Diaphorase 4; diaphorase-4; dioxin-inducible 1; DT-diaphorase; DTD; menadione reductase; NAD(P):menadione oxidoreductase; NAD(P)H dehydrogenase, quinone 1; NAD(P)H-quinone oxidoreductase; NAD(P)H:menadione oxidoreductase; NAD(P)H:menadione oxidoreductase (EC 1.6.99.2); NAD(P)H:menadione oxidoreductase 1; NAD(P)H:Quinone acceptor oxidoreductase type 1; NAD(P)H:quinone oxidoreductase 1; NAD(P)H:quinone oxireductase; NQ01; phylloquinone reductase; QR1; quinone reductase (EC 1.6.99.2); quinone reductase 1; unnamed protein product
Gene Aliases: DHQU; DIA4; DTD; NMOR1; NMORI; QR1
UniProt ID: (Human) P15559, (Rat) P05982
Entrez Gene ID: (Human) 1728, (Rat) 24314
protein polyubiquitination
ubiquinone metabolic process
xenobiotic metabolic process
nitric oxide biosynthetic process
response to oxidative stress
synaptic transmission, cholinergic
response to toxic substance
removal of superoxide radicals
protein catabolic process
response to lipopolysaccharide
cellular response to oxidative stress
negative regulation of protein catabolic process
vitamin E metabolic process
vitamin K metabolic process
innate immune response
cell redox homeostasis
negative regulation of ferroptosis
response to ischemia
superoxide metabolic process
response to nutrient
response to xenobiotic stimulus
response to hormone
response to carbohydrate
response to estradiol
response to testosterone
negative regulation of apoptotic process
negative regulation of catalytic activity
response to alkaloid
positive regulation of neuron apoptotic process
response to ethanol
response to electrical stimulus
response to caloric restriction
cellular response to hydrogen peroxide
cellular response to metal ion
positive regulation of NAD metabolic process
response to tetrachloromethane
response to L-glutamine
response to hydrogen sulfide
response to flavonoid
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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