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Proteintech
RASGRP3 Monoclonal Antibody (1A10G4), CoraLite® 594
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Product Details
CL594-66650
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1A10G4
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: SLQNASHHLE PNMDLINLLT LSLDLYHTED DIYKLSLVLE PRNSKSQPTS PTTPNKPVVP LEWALGVMPK PDPTVINKHI RKLVESVFRN YDHDHDGYIS QEDFESIAAN FPFLDSFCVL DKDQDGLISK DEMMAYFLRA KSQLHCKMGP GFIHNFQEMT YLKPTFCEHC AGFLWGIIKQ GYKCKDCGAN CHKQCKDLLV LACRRFARAP SLSSGHGSLP GSPSLPPAQD EVFEFPGVTA GHRDLDSRAI TLVTGSSRKI SVRLQRATTS QATQTEPVWS EAGWGDSGSH TFPKMKSKFH DKAAKDKGFA KWENEKPRVH AGVDVVDRGT EFELDQDEGE ETRQDGEDG
Target Information
Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calcium and DAG-regulated guanine nucleotide exchange factor III; calcium- and diacylglycerol-regulated guanine nucleotide exchange factor III; CalDAG-GEFIII; Guanine nucleotide exchange factor for Rap1; OTTHUMP00000201245; RAS guanyl releasing protein 3 (calcium and DAG-regulated); Ras guanyl-releasing protein 3; unnamed protein product
Gene Aliases: BC066069; Gm327; GRP3; KIAA0846; RASGRP3
UniProt ID: (Human) Q8IV61
Entrez Gene ID: (Human) 25780, (Mouse) 240168
guanyl-nucleotide exchange factor activity
GTPase activator activity
calcium ion binding
protein binding
zinc ion binding
kinase binding
diacylglycerol binding
GTPase regulator activity
small GTPase binding
metal ion binding
Ras guanyl-nucleotide exchange factor activity
Ras GTPase binding
guanyl-nucleotide exchange factor
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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