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Proteintech
FXYD1 Monoclonal Antibody (2C10G9), CoraLite® 594
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Product Details
CL594-67150
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
2C10G9
Immunogen
FXYD1 fusion protein Ag25307
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MASLGHILV FCVGLLTMAK AESPKEHDPF TYDYQSLQIG GLVIAGILFI LGILIVLSRR CRCKFNQQQR TGEPDEEEGT FRSSIRRLST RRR
Target Information
This gene encodes a member of the FXYD family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity and act as an accessory protein of Na,K-ATPase. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FXYD domain-containing ion transport regulator 1; Phospholemman; phospholemman transcript variant b; Sodium Potassium ATPase; Sodium/potassium-transporting ATPase subunit FXYD1; unnamed protein product
Gene Aliases: 0610012C17Rik; 1110006M24Rik; FXYD1; PLM; Pml
UniProt ID: (Human) O00168, (Mouse) Q9Z239
Entrez Gene ID: (Human) 5348, (Mouse) 56188
ion transport
potassium ion transport
sodium ion transport
chloride transport
muscle contraction
regulation of heart contraction
negative regulation of protein glutathionylation
regulation of ion transport
regulation of cardiac muscle cell membrane potential
regulation of sodium ion transmembrane transport
chloride transmembrane transport
positive regulation of sodium ion export from cell
transport
positive regulation of organic acid transport
regulation of cytosolic calcium ion concentration
regulation of cardiac muscle cell contraction
positive regulation of inorganic anion transmembrane transport
regulation of sodium ion transmembrane transporter activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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