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Proteintech
GNL3 Monoclonal Antibody (3B8F10), CoraLite® 594
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Product Details
CL594-67169
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
3B8F10
Immunogen
Recombinant Protein
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Concentration
2 mg/mL
Amount
200 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Target Information
Arylsulfatase F, also known as ARSF, is a 590 amino acid secretory protein that belongs to the sulfatase family of bone and cartilage matrix proteins. Arylsulfatase F uses calcium as a cofactor to catalyze reactions that are important in maintaining correct bone composition. The activity of Arylsulfatase F, unlike that of other family members, such as Arylsulfatase E, is not inhibited by warfarin. The gene encoding Arylsulfatase F maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E2-induced gene 3 protein; estradiol-induced nucleotide binding protein; guanine nucleotide binding protein-like 3 (nucleolar); Guanine nucleotide-binding protein-like 3; MGC800; NNP47; Novel nucleolar protein 47; Nucleolar GTP-binding protein 3; Nucleostemin; unnamed protein product
Gene Aliases: C77032; E2IG3; GNL3; NNP47; NS; Nug1
UniProt ID: (Human) Q9BVP2, (Mouse) Q8CI11, (Rat) Q811S9
Entrez Gene ID: (Human) 26354, (Mouse) 30877, (Rat) 290556
cell proliferation
regulation of cell proliferation
ribosome biogenesis
positive regulation of pri-miRNA transcription from RNA polymerase II promoter
metabolic process
stem cell division
stem cell population maintenance
positive regulation of telomere maintenance
positive regulation of protein sumoylation
positive regulation of protein localization to chromosome, telomeric region
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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