Search
Proteintech
Chromogranin A Monoclonal Antibody (3H11C11), CoraLite® 594
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 2
Chromogranin A Antibody (CL59460135100UL) in Flow
1X10^6 Neuro-2a cells were intracellularly stained with 0.4 µg CoraLite 594 Anti-Human Chromogranin A (Product # CL59460135100UL), Clone:3H11C11) (red), or 0.4 µg Mouse IgG1 Isotype Control (CL594-66360, Clone: T1F8D3F10) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
CL59460135100UL
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3H11C11
Conjugate
CoraLite® 594
CoraLite® 594
CoraLite® 594
Excitation/Emission Max
593/614 nm
Form
Liquid
Concentration
2 mg/mL
Amount
200 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
Target Information
Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: betagranin (N-terminal fragment of chromogranin A); catestatin; cgA; chromofungin; chromogranin A; chromogranin A (parathyroid secretory protein 1); chromogranin A precursor; CTNNB; DKFZp686D02253; FLJ25606; FLJ37923; MGC105435; pancreastatin; parathyroid secretory protein 1; pituitary secretory protein I; prohormone; SP-I; unnamed protein product
Gene Aliases: CGA; ChrA; PHE5; PHES
UniProt ID: (Pig) P04404, (Human) P10645, (Mouse) P26339
Entrez Gene ID: (Pig) 397540, (Human) 1113, (Mouse) 12652, (Rat) 24258
positive regulation of protein phosphorylation
regulation of the force of heart contraction
mast cell chemotaxis
protein localization to secretory granule
negative regulation of catecholamine secretion
defense response to bacterium
mast cell degranulation
mast cell activation
positive regulation of vasoconstriction
negative regulation of insulin secretion
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
regulation of cytosolic calcium ion concentration
positive regulation of cardiac muscle contraction
positive regulation of cAMP/PKA signal transduction
positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of relaxation of cardiac muscle
positive regulation of dense core granule biogenesis
ovulation cycle
mast cell cytokine production
regulation of blood pressure
innate immune response
adenylate cyclase-activating adrenergic receptor signaling pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support