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Proteintech
CHD4 Monoclonal Antibody (3D9G2), CoraLite® 594
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Product Details
CL59466222100UL
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3D9G2
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
Target Information
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent chromatin remodeler CHD4; ATP-dependent helicase CHD4; CHD-4; Chromo domain-containing protein 4; Mi-2 autoantigen 218 kDa protein; Mi2-beta; MI2B; unnamed protein product
Gene Aliases: CHD-4; CHD4; Mi-2b; Mi2-BETA; SIHIWES
UniProt ID: (Human) Q14839
Entrez Gene ID: (Human) 1108
nucleotide binding
transcription cofactor binding
DNA binding
chromatin binding
transcription corepressor activity
protein binding
ATP binding
zinc ion binding
hydrolase activity
ATPase activity
nucleosomal DNA binding
histone binding
histone deacetylase binding
metal ion binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
DNA-binding transcription factor binding
ATP-dependent chromatin remodeler activity
negative regulation of transcription from RNA polymerase II promoter
double-strand break repair via homologous recombination
chromatin organization
chromatin remodeling
negative regulation of gene expression
oxygen transport
regulation of cell fate specification
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
regulation of synapse assembly
terminal button organization
regulation of stem cell differentiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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