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Proteintech
SDHB Monoclonal Antibody (1A2A5), CoraLite® 594
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Product Details
CL59467600100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1A2A5
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
Target Information
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ92337; Ip; iron-sulfur subunit; Iron-sulfur subunit of complex II; Malate dehydrogenase [quinone] iron-sulfur subunit; OTTHUMP00000044624; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex subunit B; succinate dehydrogenase complex, subunit B, iron sulfur (Ip); succinate-ubiquinone oxidoreductase Ip subunit precursor; unnamed protein product
Gene Aliases: 0710008N11Rik; CWS2; IP; MC2DN4; PGL4; PPGL4; SDH; SDH1; SDH2; SDHB; SDHIP
UniProt ID: (Human) P21912, (Mouse) Q9CQA3, (Rat) P21913
Entrez Gene ID: (Human) 6390, (Mouse) 67680, (Rat) 298596
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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