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Proteintech
HADHB Monoclonal Antibody (1D12F4), CoraLite® 594
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Product Details
CL59467967100UL
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1D12F4
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
Target Information
This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2-enoyl-Coenzyme A (CoA) hydratase, beta subunit; 3-ketoacyl-Coenzyme A (CoA) thiolase of mitochondrial trifunctional protein, beta subunit; acetyl-CoA acyltransferase; bet; beta-ketothiolase; hydroxyacyl-Co; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit; hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta aubunit; hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit; long-chain 3-ketoacyl-CoA thiolase; mitochondrial trifunctional protein, beta subunit; small subunit of trifunctional beta-oxidation complex; TP-beta; Trifunctional enzyme subunit beta, mitochondrial; unnamed protein product
Gene Aliases: 4930479F15Rik; ECHB; HADHB; LCTHIO; MSTP029; MTPB; MTPD; MTPD2; TP-BETA
UniProt ID: (Human) P55084, (Mouse) Q99JY0, (Rat) Q60587
Entrez Gene ID: (Pig) 397017, (Human) 3032, (Mouse) 231086, (Rat) 171155
RNA binding
3-hydroxyacyl-CoA dehydrogenase activity
acetyl-CoA C-acetyltransferase activity
acetyl-CoA C-acyltransferase activity
enoyl-CoA hydratase activity
protein binding
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
macromolecular complex binding
acetyl-CoA C-myristoyltransferase activity
lncRNA binding
fatty-acyl-CoA binding
catalytic activity
long-chain-enoyl-CoA hydratase activity
long-chain-3-hydroxyacyl-CoA dehydrogenase activity
protein complex binding
poly(A) RNA binding
NAD binding
acyltransferase
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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