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RBAP48 Monoclonal Antibody (5C4D6), CoraLite® Plus 647
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FIGURE: 1 / 1
RBAP48 Antibody (CL647-66060) in Flow
1X10^6 HeLa cells were intracellularly stained with 0.2 µg CoraLite® Plus 647 Anti-Human RBAP48 (CL647-66060, Clone:5C4D6) (red), or 0.2 µg Control Antibody. Cells were fixed and permeabilized with Transcription Factor Staining Buffer Kit (PF00011).
Product Details
CL647-66060
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
5C4D6
Immunogen
Fusion Protein
Conjugate
Excitation/Emission Max
654/674 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MADKEAAFDD AVEERVINEE YKIWKKNTPF LYDLVMTHAL EWPSLTAQWL PDVTRPEGKD FSIHRLVLGT HTSDEQNHLV IASVQLPNDD AQFDASHYDS EKGEFGGFGS VSGKIEIEIK INHEGEVNRA RYMPQNPCII ATKTPSSDVL VFDYTKHPSK PDPSGECNPD LRLRGHQKEG YGLSWNPNLS GHLLSASDDH TICLWDISAV PKEGKVVDAK TIFTGHTAVV EDVSWHLLHE SLFGSVADDQ KLMIWDTRSN NTSKPSHSVD AHTAEVNCLS FNPYSEFILA TGSADKTVAL WDLRNLKLKL HSFESHKDEI FQVQWSPHNE TILASSGTDR RLNVWDLSKI GEEQSPEDAE DGPPELLFIH GGHTAKISDF SWNPNEPWVI CSVSEDNIMQ VWQMAENIYN DEDPEGSVDP EGQGS
Target Information
RbAp48-11G10 recognizes full length RbAp48, a 48 kDa nuclear protein first isolated by its ability to interact with the carboxyl-terminus of the retinoblastoma protein (Rb). It is a member of the WD (Trp-Asp) repeat family of proteins. RbAp48 is one of the three subunits of CAF-1, can bind to histone H4 and is a subunit of human histone deacetylase HD1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAF-1 p48 subunit; CAF-1 subunit C; CAF-I 48 kDa subunit; CAF-I p48; Chromatin assembly factor 1 subunit C; Chromatin assembly factor I p48 subunit; chromatin assembly factor/CAF-1 p48 subunit; Histone-binding protein RBBP4; MSI1 protein homolog; Nucleosome-remodeling factor subunit RBAP48; RBBP-4; Retinoblastoma-binding protein 4; Retinoblastoma-binding protein p48; unnamed protein product
Gene Aliases: lin-53; mRbAp48; NURF55; RBAP48; RBBP4
UniProt ID: (Human) Q09028, (Mouse) Q60972
Entrez Gene ID: (Human) 5928, (Rat) 313048, (Mouse) 19646
negative regulation of transcription from RNA polymerase II promoter
DNA replication
DNA repair
chromatin organization
nucleosome assembly
DNA replication-dependent nucleosome assembly
chromatin remodeling
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
brain development
negative regulation of cell proliferation
negative regulation of cell migration
negative regulation of transforming growth factor beta receptor signaling pathway
regulation of cell fate specification
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of stem cell population maintenance
positive regulation of stem cell population maintenance
regulation of stem cell differentiation
DNA replication-independent nucleosome assembly
metabolic process
chromatin assembly
ATP-dependent chromatin remodeling
response to growth hormone
transcription, DNA-templated
cell cycle
chromatin modification
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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