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Proteintech
ORM1/2 Monoclonal Antibody (5F2H7), CoraLite® Plus 647
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FIGURE: 1 / 1
ORM1/2 Antibody (CL647-66097) in Flow
1X10^6 HepG2 cells were intracellularly stained with 0.2 µg CoraLite® Plus 647 Anti-Human ORM1/2 (CL647-66097, Clone:5F2H7) (red), or 0.2 µg APC-65124 ; APC Mouse IgG1 Isotype Control (APC-65124, Clone: MOPC-21) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
Product Details
CL647-66097
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
5F2H7
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
654/674 nm
Form
Liquid
Purification
Protein G
Storage buffer
PBS with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: NLVPVPITNA TLDRITGKWF YIASAFRNEE YNKSVQEIQA TFFYFTPNKT EDTIFLREYQ TRQDQCIYNT TYLNVQRENG TISRYVGGQE HFAHLLILRD TKTYMLAFDV NDEKNWGLSV YADKPETTKE QLGEFYEALD CLRIPKSDVV YTDWKKDKCE PLEKQHEKER KQEEGES
Target Information
ORM1 is an acute phase plasma protein synthesized by the liver. The protein is believed to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, also regulates the extravasation of the cells during infection and inflammation. ORM1 is a major acute phase reactant, both in human and in rat. In human plasma, ORM1 (44 kDa) is found at levels of 0.5-1.4 mg/mL. Its concentration in blood plasma is elevated during acute inflammation, such as trauma, malignancies, myocardial infarction, rheumatoid arthritis, bacterial infections, after major surgery, in cases of chronic pain etc, and can be used for the diagnosis of inflammatory conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AGP 1; AGP 2; alpha-1 acid glycoprotein precursor; Alpha-1-acid glycoprotein 1; Alpha-1-acid glycoprotein 2; alpha-1-acid glycoprotein, type 2; epididymis secretory sperm binding protein Li 153w; OMD 1; OMD 2; ORM2; Orosomucoid-1; Orosomucoid-2; unnamed protein product
Gene Aliases: A1AG1; AGP-A; AGP-B; AGP-B'; AGP1; AGP2; HEL-S-153w; ORM; ORM1; ORM2
UniProt ID: (Human) P02763, (Human) P19652
Entrez Gene ID: (Human) 5004, (Human) 5005
regulation of immune system process
acute-phase response
inflammatory response
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
positive regulation of interleukin-1 beta production
positive regulation of interleukin-1 production
positive regulation of tumor necrosis factor production
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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