Immunogen sequence: MAMWQGAMDNR GFQQGSFSSF QNSSSDEDLM DIPATAMDFS MRDDVPPLDR EVG
Highest antigen sequence identity to the following orthologs - mouse 91%, rat 91%.
Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function.
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Protein Aliases: Chloride channel protein 5; chloride channel, voltage-sensitive 5; Chloride transporter ClC-5; ClC-5; H(+)/Cl(-) exchange transporter 5; hClC-K2; voltage-gated chloride ion channel CLCN5
Gene Aliases: ClC-5; CLC5; CLCK2; CLCN5; DENTS; hCIC-K2; NPHL1; NPHL2; XLRH; XRN
UniProt ID: (Human) P51795
Entrez Gene ID: (Human) 1184
Molecular Function: ion channel