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Proteintech
CLCA2 Polyclonal Antibody
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Product Details
19273-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CLCA2 Fusion Protein Ag5914 (595-901 aa encoded by BC041096)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Amount
31.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SRASNSAVP PATVEAFVER DSLHFPHPVM IYANVKQGFY PILNATVTAT VEPETGDPVT LRLLDDGAGA DVIKNDGIYS RYFFSFAANG RYSLKVHVNH SPSISTPAHS IPGSHAMYVP GYTANGNIQM NAPRKSVGRN EEERKWGFSR VSSGGSFSVL GVPAGPHPDV FPPCKIIDLE AVKVEEELTL SWTAPGEDFD QGQATSYEIR MSKSLQNIQD DFNNAILVNT SKRNPQQAGI REIFTFSPQI STNGPEHQPN GETHESHRIY VAIRAMDRNS LQSAVSNIAQ APLFIPPNSD PVPARDYL (595-901 aa encoded by BC041096)
Target Information
The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: bovine epithelial chloride channel homolog; CaCC-3; Calcium-activated chloride channel family member 2; Calcium-activated chloride channel family member 5; Calcium-activated chloride channel protein 3; Calcium-activated chloride channel regulator 2; chloride channel calcium activated 5; chloride channel, calcium activated, family member 2; CLCA family member 2, chloride channel regulator; FLJ97885; hCLCA2; mCLCA5; unnamed protein product
Gene Aliases: 4732440A06; AI586120; CACC; CaCC-3; CACC3; CLCA2; Clca5; CLCRG2
UniProt ID: (Human) Q9UQC9, (Mouse) Q8BG22
Entrez Gene ID: (Human) 9635, (Mouse) 229933
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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