Immunogen sequence: GVDHAYVTSI GRLIGIVTLK ELRKAIEGSV TAQGVKVRPP LASFRDSATS SSDTETTEVH ALWGPHSRHG
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
The transmembrane protein encoded by this gene is a voltage-gated chloride channel that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: chloride channel 2; Chloride channel protein 2; chloride channel, voltage-sensitive 2; CIC-2; ClC-2; CLCN2; ECA2; ECA3; EGI11; EGI3; EGMA; EJM6; EJM8; Epilepsy, idiopathic generalized, susceptibility to
Gene Aliases: CIC-2; clC-2; CLC2; CLCN2; ECA2; ECA3; EGI11; EGI3; EGMA; EJM6; EJM8; LKPAT
UniProt ID: (Human) P51788
Entrez Gene ID: (Human) 1181