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CLCN7 Polyclonal Antibody
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Product Details
OSC00148W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 250-300 of human CLCN7 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The antigen is homologous in rat and mouse.
Specificity of this antibody: CLCN7.
Target Information
The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Chloride channel 7 alpha subunit; Chloride channel protein 7; chloride channel, voltage-sensitive 7; CLC-7; CLCN-7; H(+)/Cl(-) exchange transporter 7; protein phosphatase 1, regulatory subunit 63; unnamed protein product
Gene Aliases: AA409691; AW538136; CLC-7; CLC7; CLCN7; D17Wsu51e; HOD; OPTA2; OPTB4; PPP1R63
UniProt ID: (Human) P51798, (Rat) P51799, (Mouse) O70496
Entrez Gene ID: (Human) 1186, (Rat) 29233, (Mouse) 26373
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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