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Proteintech
CLEC14A Polyclonal Antibody
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Product Details
23964-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CLEC14A Fusion Protein Ag21081 (1-349 aa encoded by BC031567)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MRPAFALCL LWQALWPGPG GGEHPTADRA GCSASGACYS LHHATMKRQA AEEACILRGG ALSTVRAGAE LRAVLALLRA GPGPGGGSKD LLFWVALERR RSHCTLENEP LRGFSWLSSD PGGLESDTLQ WVEEPQRSCT ARRCAVLQAT GGVEPAGWKE MRCHLRANGY LCKYQFEVLC PAPRPGAASN LSYRAPFQLH SAALDFSPPG TEVSALCRGQ LPISVTCIAD EIGARWDKLS GDVLCPCPGR YLRAGKCAEL PNCLDDLGGF ACECATGFEL GKDGRSCVTS GEGQPTLGGT GVPTRRPPAT ATSPVPQRTW PIRVDEKLGE TPLVPEQDNS VTSIPEIPRW (1-349 aa encoded by BC031567)
Target Information
CLEC-14A (C-type lectin domain family 14 member A), also known as EGFR-5 (epidermal growth factor receptor 5) or CEG1, is a 490 amino acid single-pass type I membrane protein that contains one C-type lectin domain and an EGF-like domain. The gene encoding CLEC-14A maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder alpha1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C-type lectin domain family 14 member A; C-type lectin domain family 14, member A; ClECT and EGF-like domain containing protein; EGFR-5; Epidermal growth factor receptor 5
Gene Aliases: 1200003C23Rik; AI642649; C14orf27; CEG1; CLEC14A; EGFR-5; EGFR5; UNQ236/PRO269
UniProt ID: (Human) Q86T13, (Mouse) Q8VCP9
Entrez Gene ID: (Human) 161198, (Mouse) 66864
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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