Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: HMKCFLAFT QTKTFHEASE DCISRGGTLS TPQTGSENDA LYEYLRQSVG NEAEIWLGLN DMAAEGTWVD MTGARIAYKN WETEITAQPD GGKTENCAVL SGAANGKWFD KRCRDQLPYI CQFGIV (78-202 aa encoded by BC011024)
Tetranectin (TN) is a serum and tissue protein, a C-type lectin, which binds to Ca++. It is a homotrimer of monomers each with a mass of 20 kDa, plasma or serum concentrations of TN are found to be approximately 10 mg/l. In vitro, TN can bind to kringle 4 of plasminogen and enhance the activation of plaminogen to plasmin, catalyzed by tissue plasminogen activator in the presence of poly-D-lysine. TN is best known as a prognostic marker in ovarian cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-type lectin domain family 3 member B; C-type lectin domain family 3, member B; Plasminogen kringle 4-binding protein; Tetranectin; tetranectin (plasminogen binding protein); tetranectin (plasminogen-binding protein); TN
Gene Aliases: CLEC3B; TN; TNA
UniProt ID: (Human) P05452
Entrez Gene ID: (Human) 7123, (Mouse) 21922
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