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Invitrogen
CLIC2 Polyclonal Antibody
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Product Details
PA5-41005
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the C-terminal of human CLIC2 (aa 162-211).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: SAEEPPVSRR LFLDGDQLTL ADCSLLPKLN IIKVAAKKYR DFDIPAEFSG
Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 79%; Rabbit: 100%; Rat: 100%
Target Information
Chloride intracellular channel 2 is a member of the p64 family, a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. CLIon Channel 2 encodes a protein that is detected in fetal liver and adult skeletal muscle tissue. CLIon Channel2 maps to the candidate region on chromosome X for incontinentia pigmenti.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chloride intracellular channel protein 2; Glutaredoxin-like oxidoreductase CLIC2; Glutaredoxin-like peroxidase CLIC2; XAP121
Gene Aliases: CLIC2; CLIC2b; MRXS32; XAP121
UniProt ID: (Human) O15247
Entrez Gene ID: (Human) 1193
glutathione metabolic process
transport
signal transduction
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
positive regulation of binding
negative regulation of ryanodine-sensitive calcium-release channel activity
cellular oxidant detoxification
chloride transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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