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Invitrogen
CLIC4 Polyclonal Antibody
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FIGURE: 1 / 6
CLIC4 Antibody (PA5-116469) in IHC (P)
Immunohistochemical analysis of CLIC4 in a paraffin-embedded rat skeletal muscle tissue using a CLIC4 polyclonal antibody (Product #PA5-116469). The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (1:100) ... View More
Product Details
PA5-116469
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within Human CLIC4 aa 1-50.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 0.2% BSA, 50% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive controls: Rat kidney and mouse kidney tissue lysates, rat skeletal muscle tissue, human kidney tissue, human placenta tissue, mouse heart tissue, 293T.
Target Information
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: chloride intracellular channel 4 (mitochondrial); chloride intracellular channel 4 like; Chloride intracellular channel protein 4; DKFZP566G223; FLJ38640; Glutaredoxin-like oxidoreductase CLIC4; Intracellular chloride ion channel protein p64H1; mc3s5/mtCLIC; mitochondrial chloride intracellular channel 4
Gene Aliases: CLIC4; CLIC4L; D0Jmb3; H1; huH1; mc3s5; MTCLIC; p64H1; TU-74
UniProt ID: (Human) Q9Y696, (Mouse) Q9QYB1, (Rat) Q9Z0W7
Entrez Gene ID: (Human) 25932, (Mouse) 29876, (Rat) 83718
angiogenesis
endothelial cell morphogenesis
glutathione metabolic process
chloride transport
apoptotic process
vacuolar acidification
fertilization
cell differentiation
keratinocyte differentiation
negative regulation of cell migration
regulation of ion transmembrane transport
establishment or maintenance of apical/basal cell polarity
multicellular organism growth
branching morphogenesis of an epithelial tube
regulation of cytoskeleton organization
retina vasculature morphogenesis in camera-type eye
cellular response to calcium ion
chloride transmembrane transport
transport
ion transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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