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Invitrogen
CLK2 Polyclonal Antibody
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FIGURE: 1 / 1
CLK2 Antibody (PA5-96845) in WB
Western blot analysis of CLK2 in extracts of various cell lines. Samples were incubated with CLK2 Polyclonal antibody (Product # PA5-96845) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-96845
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 239-498 of human CLK2 (NP_0039842)
Conjugate
Form
Liquid
Concentration
1.36 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: CISFELLGLS TFDFLKDNNY LPYPIHQVRH MAFQLCQAVK FLHDNKLTHT DLKPENILFV NSDYELTYNL EKKRDERSVK STAVRVVDFG SATFDHEHHS TIVSTRHYRA PEVILELGWS QPCDVWSIGC IIFEYYVGFT LFQTHDNREH LAMMERILGP IPSRMIRKTR KQKYFYRGRL DWDENTSAGR YVRENCKPLR RYLTSEAEEH HQLFDLIESM LEYEPAKRLT LGEALQHPFF ARLRAEPPNK LWDSSRDISR; Positive Samples: BT-474, HeLa, Mouse brain, Mouse lung; Cellular Location: Nucleus, Nucleus speckle, Nucleus speckle
Target Information
CLK2 is a serine/threonine kinase that phosphorylates serine/arginine-rich proteins as related to controlling RNA splicing. It is also thought to link cell cycle progression, apoptosis, and telomere length regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDC-like kinase 2; CLK kinase; Clk2-Scamp3 protein; Dual specificity protein kinase CLK2; EC 2.7.12.1; hCLK2; kinase CLK2; Protein kinase CLK2
Gene Aliases: AU041688; CLK2; Tu52
UniProt ID: (Human) P49760, (Mouse) O35491
Entrez Gene ID: (Human) 1196, (Rat) 365842, (Mouse) 12748
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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