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CLN8 Polyclonal Antibody
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FIGURE: 1 / 2
CLN8 Antibody (BS-11715R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded rat brain; Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20min; Antibody incubation with Rabbit Anti-CLN8 Polyclonal Antibody, Unconjugated (bs-11715R) at 1:500 overnight at 4°C, followed by a conjugated secondary for 90 minute... View More
Product Details
BS-11715R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human CLN8, amino acids 201-286.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Could play a role in cell proliferation during neuronal differentiation and in protection against cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ceroid-lipofuscinosis, neuronal 8; motor neuron degeneration; Protein CLN8; unnamed protein product
Gene Aliases: C8orf61; CLN8; EPMR; mnd; TLCD6
UniProt ID: (Human) Q9UBY8, (Mouse) Q9QUK3, (Rat) Q6AYM9
Entrez Gene ID: (Human) 2055, (Mouse) 26889, (Rat) 306619
age-dependent response to oxidative stress
phospholipid metabolic process
ceramide metabolic process
mitochondrial membrane organization
lysosome organization
nervous system development
visual perception
adult walking behavior
cholesterol metabolic process
associative learning
adult locomotory behavior
regulation of cell size
spinal cord motor neuron differentiation
somatic motor neuron differentiation
social behavior
negative regulation of apoptotic process
cellular protein catabolic process
cellular macromolecule catabolic process
cellular protein metabolic process
photoreceptor cell maintenance
musculoskeletal movement
neuromuscular process controlling posture
neuromuscular process controlling balance
negative regulation of transferase activity
glutamate reuptake
retina development in camera-type eye
neurofilament cytoskeleton organization
biological_process
lipid transport
apoptotic process
lipid biosynthetic process
macromolecule catabolic process
protein catabolic process
negative regulation of neuron apoptotic process
negative regulation of proteolysis
ceramide biosynthetic process
neuron apoptotic process
lipid homeostasis
retinal rod cell apoptotic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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