Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA1-521 detects CLOCK from cells transfected with the mouse CLOCK gene.
PA1-521 has been sucessfully used in Western blot procedures. By Western blot, this antibody detects an ~100 kDa protein representing CLOCK from cells transfected with the mouse CLOCK gene.
The PA1-521 immunogen is a synthetic peptide corresponding to residues C S(394) L P E T A A D K S Q D S G S D N (410) of mouse CLOCK. This sequence is completely conserved between mouse and human CLOCK. PA1-521 immunizing peptide (Cat. # PEP-073) is available for use in neutralization and control experiments.
This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Circadian locomoter output cycles protein kaput; mCLOCK
Gene Aliases: Clock
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support