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Proteintech
CLTC Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
26523-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CLTC Fusion Protein Ag25041 (1-351 aa encoded by BC054489)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.3 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAQILPIRF QEHLQLQNLG INPANIGFST LTMESDKFIC IREKVGEQAQ VVIIDMNDPS NPIRRPISAD SAIMNPASKV IALKAGKTLQ IFNIEMKSKM KAHTMTDDVT FWKWISLNTV ALVTDNAVYH WSMEGESQPV KMFDRHSSLA GCQIINYRTD AKQKWLLLTG ISAQQNRVVG AMQLYSVDRK VSQPIEGHAA SFAQFKMEGN AEESTLFCFA VRGQAGGKLH IIEVGTPPTG NQPFPKKAVD VFFPPEAQND FPVAMQISEK HDVVFLITKY GYIHLYDLET GTCIYMNRIS GETIFVTAPH EATAGIIGVN RKGQVLSVCV EEENIIPYIT NVLQNPDLAL RM (1-351 aa encoded by BC054489)
Target Information
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: clathrin heavy chain; clathrin heavy chain on chromosome 17; clathrin heavy chain on chromosome 22; clathrin, heavy chain (Hc); clathrin, heavy polypeptide (Hc); Clathrin, heavy polypeptide D; clathrin, heavy polypeptide-like 1; clathrin, heavy polypeptide-like 2; CLH-22; KIAA0034; unnamed protein product
Gene Aliases: 3110065L21Rik; CHC; CHC17; CHC22; CLH-17; CLH22; CLTCL; CLTCL2; CLTD; Hc; MRD56
UniProt ID: (Human) Q00610, (Human) P53675, (Mouse) Q68FD5, (Rat) P11442
Entrez Gene ID: (Human) 1213, (Pig) 100271929, (Human) 8218, (Mouse) 67300, (Rat) 54241
RNA binding
double-stranded RNA binding
structural molecule activity
protein binding
protein kinase binding
clathrin light chain binding
low-density lipoprotein particle receptor binding
disordered domain specific binding
ubiquitin-specific protease binding
ankyrin binding
heat shock protein binding
peptide binding
protein serine/threonine kinase binding
vesicle coat protein
mitotic cell cycle
osteoblast differentiation
intracellular protein transport
receptor-mediated endocytosis
mitotic spindle organization
chromosome segregation
vesicle-mediated transport
receptor internalization
transferrin transport
retrograde transport, endosome to Golgi
clathrin coat assembly
regulation of mitotic spindle organization
clathrin coat disassembly
clathrin-mediated endocytosis
amyloid-beta clearance by transcytosis
negative regulation of hyaluronan biosynthetic process
negative regulation of protein localization to plasma membrane
anatomical structure morphogenesis
positive regulation of glucose import
Golgi organization
synaptic vesicle endocytosis
mitotic spindle assembly
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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