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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • ICMT Antibodies

          Fabgennix

          CMT Polyclonal Antibody

          View all (10) ICMT antibodies

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          Cite CMT Polyclonal Antibody

          • Antibody Testing Data (1)
          CMT Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.
          CMT Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          CMT Antibody (ICMT-101AP) in IHC

          Mouse Kidney- CMT Primary Antibody: ICMT-101AP; 1:50 dilution in IHC Blocking Buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 20X magnification. FFPE section. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CMT Antibody in Immunohistochemistry (IHC)
          CMT Polyclonal Antibody

          Product Details

          ICMT-101AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunohistochemistry (IHC)

          1:50-1:250
          -

          ELISA (ELISA)

          1:10,000
          -

          Immunoprecipitation (IP)

          1:50-1:250
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide taken within amino acid region 230-284 on human Protein-S-isoprenylcysteine O-methyltransferase.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5-1.5 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          This gene encodes the third of three enzymes that post translationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: Farnesyl cysteine carboxyl methyltransferase; FCMT; Isoprenylcysteine carboxylmethyltransferase; MGC39955; pcCMT; PPMT; Prenylated protein carboxyl methyltransferase; prenylcysteine carboxyl methlytransferase; Prenylcysteine carboxyl methyltransferase; protein-S isoprenylcysteine O-methyltransferase; Protein-S-isoprenylcysteine O-methyltransferase

          View more View less

          Gene Aliases: 1700008E11Rik; C80758; fcmt; Gm13095; HSTE14; ICMT; MST098; MSTP098; OTTMUSG00000010406; PCCMT; PCMT; PPMT; STE14

          View more View less

          UniProt ID: (Human) O60725, (Rat) Q9WVM4, (Mouse) Q9EQK7

          View more View less

          Entrez Gene ID: (Human) 23463, (Rat) 170818, (Mouse) 57295

          View more View less

          Function(s)
          protein C-terminal carboxyl O-methyltransferase activity protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity cAMP response element binding protein binding methyltransferase activity transferase activity protein modifying enzyme
          Process(es)
          cellular protein modification process C-terminal protein methylation protein targeting to membrane post-translational protein modification S-adenosylhomocysteine metabolic process S-adenosylmethioninamine metabolic process in utero embryonic development liver development protein methylation protein localization positive regulation of cell proliferation multicellular organism growth regulation of Ras protein signal transduction regulation of nucleic acid-templated transcription regulation of RNA biosynthetic process methylation
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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