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This gene encodes the third of three enzymes that post translationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.
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Protein Aliases: Farnesyl cysteine carboxyl methyltransferase; FCMT; Isoprenylcysteine carboxylmethyltransferase; MGC39955; pcCMT; PPMT; Prenylated protein carboxyl methyltransferase; prenylcysteine carboxyl methlytransferase; Prenylcysteine carboxyl methyltransferase; protein-S isoprenylcysteine O-methyltransferase; Protein-S-isoprenylcysteine O-methyltransferase
Gene Aliases: 1700008E11Rik; C80758; fcmt; Gm13095; HSTE14; ICMT; MST098; MSTP098; OTTMUSG00000010406; PCCMT; PCMT; PPMT; STE14
UniProt ID: (Human) O60725, (Rat) Q9WVM4, (Mouse) Q9EQK7
Entrez Gene ID: (Human) 23463, (Rat) 170818, (Mouse) 57295
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