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Proteintech
CNBP Polyclonal Antibody
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Product Details
14717-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CNBP Fusion Protein Ag6441 (1-170 aa encoded by BC000288)
Conjugate
Form
Liquid
Concentration
0.48 mg/mL
Amount
72 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSSNECFKC GRSGHWAREC PTGGGRGRGM RSRGRGFQFV SSSLPDICYR CGESGHLAKD CDLQEDACYN CGRGGHIAKD CKEPKREREQ CCYNCGKPGH LARDCDHADE QKCYSCGEFG HIQKDCTKVK CYRCGETGHV AINCSKTSEV NCYRCGESGH LARECTIEAT A (1-170 aa encoded by BC000288)
Target Information
This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CCHC-type zinc finger nucleic acid binding protein; cellular nucleic acid binding protein 1; Cellular nucleic acid-binding protein; CNBP; erythroid differentiation-related; HGNC:13164; sterol regulatory element-binding protein; unnamed protein product; zinc finger protein; zinc finger protein 273; Zinc finger protein 9; zinc finger protein 9 (a cellular retroviral nucleic acid binding protein); zinc finger protein; hCNBP
Gene Aliases: AA408710; CNBP; CNBP1; DM2; PROMM; RNF163; ZCCHC22; ZNF9
UniProt ID: (Human) P62633, (Mouse) P53996
Entrez Gene ID: (Human) 7555, (Mouse) 12785
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
positive regulation of cell proliferation
cholesterol homeostasis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
G-quadruplex DNA formation
positive regulation of cytoplasmic translation
transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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