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Proteintech
CNGA4 Polyclonal Antibody
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Product Details
22201-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CNGA4 fusion protein Ag17481
Conjugate
Form
Liquid
Concentration
0.65 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: TIMGSMSSVI YNMNTADAAF YPDHALVKKY MKLQHVNRKL ERRVIDWYQH LQINKKMTNE VAILQHLPER LRAEVAVSVH LSTLSRVQIF QNCEASLLEE LVLKLQPQTY SPGEYVCRKG DIGQEMYIIR EGQLA
Target Information
Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CNCalpha4, CNG5; cng channel; CNG channel alpha-4; CNG-4; CNG4; cyclic nucleotide gated cation channel; cyclic nucleotide-gated cation channel alpha 4; cyclic nucleotide-gated cation channel alpha-4; Cyclic nucleotide-gated channel alpha-4; cyclic nucleotide-gated olfactory channel subunit OCNC2; OCNC2; olfactory cyclic nucleotide-gated channel; Olfactory cyclic nucleotide-gated channel subunit 2
Gene Aliases: Cgn2; Cnga4; rOCNC2
UniProt ID: (Mouse) Q3UW12, (Rat) Q64359
Entrez Gene ID: (Mouse) 233649, (Rat) 85258
nucleotide binding
ion channel activity
intracellular cyclic nucleotide activated cation channel activity
intracellular cAMP activated cation channel activity
intracellular cGMP activated cation channel activity
voltage-gated potassium channel activity
cAMP binding
cGMP binding
ligand-gated ion channel
transport
ion transport
sensory perception of smell
ion transmembrane transport
regulation of ion transmembrane transport
regulation of membrane potential
response to stimulus
protein heterotetramerization
transmembrane transport
potassium ion transmembrane transport
cation transmembrane transport
phototransduction, visible light
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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