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Product Details
PA5-145067
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 514-567. Recombinant protein control fragment (Product #RP-109765).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3091934
Product Specific Information
Immunogen sequence: LLAELESSAL KIAYRIERLE WQTREWPMPE DLAEADDEGE PEEGTSKDEE GRAS
Antigen sequence identity: Mouse 83%; Rat 87%
Target Information
Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cng channel; CNG channel alpha-4; cyclic nucleotide gated channel beta 2; Cyclic nucleotide-gated channel alpha-4; OCNC2; Olfactory cyclic nucleotide-gated channel subunit 2
Gene Aliases: CNCA2; CNG-4; CNG4; CNG5; CNGA4; CNGB2; OCNC2; OCNCb; OCNCBETA
UniProt ID: (Human) Q8IV77
Entrez Gene ID: (Human) 1262
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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