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Immunogen sequence: PKVPRTPPAE ELAEPQAAGG GQKKGDKAPG GGGANLKGDR SRLLRDLRVD TKSRAAWARL LQEHPNARKY KGANKKGLSK GCFGLKLDRI GSMSGLGC
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 95%.
NPPC (Natriuretic Peptide C) is a hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. The protein may also be vasoactive and natriuretic. It specifically binds and stimulates the cGMP production of the NPR2 receptor, and also binds the clearance receptor NPR3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-type natriuretic peptide; CNP-22; CNP-29; CNP-53; INT3; natriuretic peptide precursor type C; NOTCH3
Gene Aliases: CNP; CNP2; NPPC
UniProt ID: (Human) P23582
Entrez Gene ID: (Human) 4880
Molecular Function:
peptide hormone
signaling molecule
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