This target displays homology in the following species: Cow: 93%; Dog: 93%; Goat: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Sheep: 93%
NPPC (Natriuretic Peptide C) is a hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. The protein may also be vasoactive and natriuretic. It specifically binds and stimulates the cGMP production of the NPR2 receptor, and also binds the clearance receptor NPR3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-type natriuretic peptide; CNP-22; CNP-29; CNP-53; INT3; natriuretic peptide precursor C; natriuretic peptide precursor type C; NOTCH3
Gene Aliases: CNP; lbab; Nppc
UniProt ID: (Mouse) Q61839
Entrez Gene ID: (Mouse) 18159
Molecular Function: peptide hormone