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COL11A2 Antibody (PA5-85501) in WB
Western blot analysis of COL11A2 in A) 293T whole cell lysate, B) whole cell lysate of human COL11A2-transfected 293T cells (partial fragment) using COL11A2 polyclonal antibody (Product # PA5-85501) using 30 µg of sample at a dilution of 1:5000. Prior to incubation with primary antibody, the sample was separated on 12% SDS-PAGE.
Product Details
PA5-85501
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human COL11A2.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792641
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (85%), Rat (85%), Bovine (93%).
Positive Control: human COL11A2-transfected 293T cells (partial fragment).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Collagen alpha-2(XI) chain; collagen, type XI, alpha 2; DAQB-79P13.8; HGNC:2187; pro-a2 chain of collagen type XI
Gene Aliases: COL11A2; DFNA13; DFNB53; FBCG2; HKE5; PARP; STL3
UniProt ID: (Human) P13942
Entrez Gene ID: (Human) 1302
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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