For Western Blot, this antibody has non-specific bands at 65 kDa.
This antibody is predicted to react with rat, horse, cow, dog and chimpanzee based on sequence homology.
The protein encoded by this gene is a noncollagenous extracellular matrix protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia and multiple epiphyseal dysplasia .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cartilage oligomeric matrix protein; cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple); cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia 1, multiple); COMP; EDM1, EPD1, MED, MGC131819, MGC149768, PSACH, THBS5, TSP5; pseudoachondroplasia (epiphyseal dysplasia 1, multiple); Thrombospondin-5; TSP5
Gene Aliases: COMP; EDM1; EPD1; MED; PSACH; THBS5; TSP5