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Invitrogen
COQ7 Polyclonal Antibody
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Product Details
PA5-76261
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein of human COQ7.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
The protein encoded by this gene is similar to a mitochondrial di-iron containing hydroxylase in Saccharomyces cerevisiae that is involved with ubiquinone biosynthesis. Mutations in the yeast gene lead to slower development and longer life span. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-demethoxyubiquinone 3-hydroxylase (NADH); CLK-1; Coenzyme q (ubiquinone) biosynthetic enzyme (DHPB methyltransferase) 7; coenzyme Q biosynthesis protein 7 homolog; coenzyme Q7 homolog, ubiquinone; COQ7 coenzyme Q, 7 homolog ubiquinone; demethyl-Q 7; DMQ hydroxylase; NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial; placental protein KG-20; Timing protein clk-1 homolog; Ubiquinone biosynthesis monooxygenase COQ7; ubiquinone biosynthesis protein COQ7 homolog; unnamed protein product
Gene Aliases: CAT5; CLK-1; CLK1; COQ10D8; COQ7; HMNR9
UniProt ID: (Human) Q99807, (Rat) Q63619, (Mouse) P97478
Entrez Gene ID: (Human) 10229, (Rat) 25249, (Mouse) 12850
chromatin binding
monooxygenase activity
protein binding
2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
metal ion binding
3-demethoxyubiquinone 3-hydroxylase (NADH) activity
molecular_function
age-dependent response to oxidative stress
in utero embryonic development
neural tube formation
ubiquinone biosynthetic process
response to oxidative stress
determination of adult lifespan
neurogenesis
respiratory electron transport chain
cellular response to oxidative stress
response to drug
mitochondrial ATP synthesis coupled electron transport
oxidation-reduction process
mitochondrion morphogenesis
negative regulation of transcription from RNA polymerase II promoter
regulation of gene expression
positive regulation of transcription from RNA polymerase II promoter
regulation of reactive oxygen species metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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