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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • C1GALT1C1 Antibodies

          Proteintech

          COSMC Polyclonal Antibody

          7 References
          View all (7) C1GALT1C1 antibodies

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          Cite COSMC Polyclonal Antibody

          • Antibody Testing Data (6)
          COSMC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          COSMC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 6

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          COSMC Antibody (19254-1-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using 19254-1-AP ( COSMC antibody at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          COSMC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          COSMC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          COSMC Antibody in Western Blot (WB)
          COSMC Antibody in Western Blot (WB)
          COSMC Antibody in Western Blot (WB)
          COSMC Antibody in Western Blot (WB)
          COSMC Polyclonal Antibody

          Product Details

          19254-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 5 publications 5 publications

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          COSMC Fusion Protein Ag6899 (1-318 aa encoded by BC050441)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MLSESSSFL KGVMLGSIFC ALITMLGHIR IGHGNRMHHH EHHHLQAPNK EDILKISEDE RMELSKSFRV YCIILVKPKD VSLWAAVKET WTKHCDKAEF FSSENVKVFE SINMDTNDMW LMMRKAYKYA FDKYRDQYNW FFLARPTTFA IIENLKYFLL KKDPSQPFYL GHTIKSGDLE YVGMEGGIVL SVESMKRLNS LLNIPEKCPE QGGMIWKISE DKQLAVCLKY AGVFAENAED ADGKDVFNTK SVGLSIKEAM TYHPNQVVEG CCSDMAVTFN GLTPNQMHVM MYGVYRLRAF GHIFNDALVF LPPNGSDND (1-318 aa encoded by BC050441 )

          Target Information

          This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: beta 1,3-galactosyltransferase 2; beta1,3-galactosyltransferase 2; C1Gal-T2; C1GALT1-specific chaperone 1; C38H2-L1; C38H2-like protein 1; Core 1 beta1,3-galactosyltransferase 2; core 1 beta3-Gal-T2; Core 1 beta3-galactosyltransferase-specific molecular chaperone; core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 2; mC1Gal-T2

          View more View less

          Gene Aliases: 1500002I11Rik; AB030184; C1GALT1C1; C1GALT2; C38H2-L1; C81205; COSMC; HSPC067; MST143; MSTP143; RGD1311230; TNPS; UNQ273/PRO310

          View more View less

          UniProt ID: (Human) Q8WWS3, (Mouse) Q9JMG2, (Rat) Q499P3

          View more View less

          Entrez Gene ID: (Human) 29071, (Mouse) 59048, (Rat) 302499

          View more View less

          Function(s)
          protein binding glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity molecular_function transferase
          Process(es)
          protein O-linked glycosylation O-glycan processing O-glycan processing, core 1 platelet activation platelet morphogenesis positive regulation of transferase activity
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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