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          • Primary Antibodies ›
          • COX15 Antibodies

          Proteintech

          COX15 Polyclonal Antibody

          2 References
          View all (7) COX15 antibodies

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          Cite COX15 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (6)
          COX15 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          COX15 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 6

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          COX15 Antibody (11441-1-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded human heart using 11441-1-AP (COX15 antibody) at dilution of 1:100 (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          COX15 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          COX15 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          COX15 Antibody in Western Blot (WB)
          COX15 Antibody in Western Blot (WB)
          COX15 Antibody in Western Blot (WB)
          COX15 Antibody in Western Blot (WB)
          COX15 Polyclonal Antibody

          Product Details

          11441-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          View 2 publications 2 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          COX15 Fusion Protein Ag2004 (1-410 aa encoded by BC002382)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.33 mg/mL

          Amount

          49.5 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MQRLLFPPL RALKGRQYLP LLAPRAAPRA QCDCIRRPLR PGQYSTISEV ALQSGRGTVS LPSKAAERVV GRWLLVCSGT VAGAVILGGV TRLTESGLSM VDWHLIKEMK PPTSQEEWEA EFQRYQQFPE FKILNHDMTL TEFKFIWYME YSHRMWGRLV GLVYILPAAY FWRKGWLSRG MKGRVLALCG LVCFQGLLGW YMVKSGLEEK SDSHDIPRVS QYRLAAHLGS ALVLYCASLW TSLSLLLPPH KLPETHQLLQ LRRFAHGTAG LVFLTALSGA FVAGLDAGLV YNSFPKMGES WIPEDLFTFS PILRNVFENP TMVQFDHRIL GITSVTAITV LYFLSRRIPL PRRTKMAAVT LLALAYTQVG LGISTLLMYV PTPLAATHQS GSLALLTGAL WLMNELRRVP K (1-410 aa encoded by BC002382)

          Target Information

          The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX15 (cytochrome c oxidase assembly protein COX15 homolog) is a 410 amino acid multi-pass mitochondrial membrane protein belonging to the COX15/ctaA family. Existing as two alternatively spliced isoforms, COX15 is predominantly expressed in tissues containing high rates of oxidative phosphorylation including brain, heart and muscle. COX15 defects are the cause of a neurodegenerative disorder known as Leigh syndrome and cytochrome c oxidase deficiency (COX deficiency).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: COX15 homolog, cytochrome c oxidase assembly protein; COX15, cytochrome c oxidase assembly homolog; cytochrome c oxidase assembly homolog 15; Cytochrome c oxidase assembly protein COX15 homolog; cytochrome c oxidase subunit 15; HAS; Heme A synthase COX15; unnamed protein product

          View more View less

          Gene Aliases: 2900026G05Rik; CEMCOX2; COX15; HAS; MC4DN6

          View more View less

          UniProt ID: (Human) Q7KZN9, (Mouse) Q8BJ03

          View more View less

          Entrez Gene ID: (Human) 1355, (Mouse) 226139

          View more View less

          Function(s)
          protein binding oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor heme binding metal ion binding heme A synthase activity cytochrome-c oxidase activity chaperone
          Process(es)
          heme biosynthetic process heme a biosynthetic process cytochrome complex assembly respiratory chain complex IV assembly oxidation-reduction process hydrogen ion transmembrane transport
          It has to be done as per old AB suggested Products section.

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