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Proteintech
CP110 Polyclonal Antibody
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Product Details
12780-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat,
Xenopus
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CP110 Fusion Protein Ag3489 (1-337 aa encoded by BC036654)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Amount
40.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MEEYEKFCE KSLARIQEAS LSTESFLPAQ SESISLIRFH GVAILSPLLN IEKRKEMQQE KQKALDVEAR KQVNRKKALL TRVQEILDNV QVRKAPNASD FDQWEMETVY SNSEVRNLNV PATFPNSFPS HTEHSTAAKL DKIAGILPLD NEDQCKTDGI DLARDSEGFN SPKQCDSSNI SHVENEAFPK TSSATPQETL ISDGPFSVNE QQDLPLLAEV IPDPYVMSLQ NLMKKSKEYI EREQSRRSLR GSMNRIVNES HLDKEHDAVE VADCVKEKGQ LTGKHCVSVI PDKPSLNKSN VLLQGASTQA SSMSMPVLAS FSKVDIPIRT GHPTVLES (1-337 aa encoded by BC036654)
Target Information
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: centriolar coiled-coil protein 110kDa; Centriolar coiled-coil protein of 110 kDa; Centriolin; centrosomal protein CP110; Centrosomal protein of 110 kDa; CEP1; Cep110; CNTRL; CP110; FAN; KIAA0419; unnamed protein product
Gene Aliases: 6330503K22Rik; AA415922; AI427129; AW557948; CCP110; CEP110; CP110; KIAA0419; RGD1310509
UniProt ID: (Human) O43303, (Mouse) Q7TSH4
Entrez Gene ID: (Human) 9738, (Dog) 479826, (Mouse) 101565, (Rat) 361634
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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