Product References
Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis.
Nature communications
Tu HQ,Qin XH,Liu ZB,Song ZQ,Hu HB,Zhang YC,Chang Y,Wu M,Huang Y,Bai YF,Wang G,Han QY,Li AL,Zhou T,Liu F,Zhang XM,Li HY
Tue Dec 11 00:00:00 EST 2018
Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication.
Cell reports
Ling H,Peng L,Wang J,Rahhal R,Seto E
Tue Dec 04 00:00:00 EST 2018
The dual role of the centrosome in organizing the microtubule network in interphase.
EMBO reports
Gavilan MP,Gandolfo P,Balestra FR,Arias F,Bornens M,Rios RM
Thu Nov 01 00:00:00 EDT 2018
Targeting USP7 Identifies a Metastasis-Competent State within Bone Marrow-Resident Melanoma CTCs.
Cancer research
Vishnoi M,Boral D,Liu H,Sprouse ML,Yin W,Goswami-Sewell D,Tetzlaff MT,Davies MA,Oliva ICG,Marchetti D
Sat Sep 15 00:00:00 EDT 2018
PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN.
eLife
Sydor AM,Coyaud E,Rovelli C,Laurent E,Liu H,Raught B,Mennella V
Fri Aug 31 00:00:00 EDT 2018
Basal exon skipping and nonsense-associated altered splicing allows bypassing complete CEP290 loss-of-function in individuals with unusually mild retinal disease.
Human molecular genetics
Barny I,Perrault I,Michel C,Soussan M,Goudin N,Rio M,Thomas S,Attié-Bitach T,Hamel C,Dollfus H,Kaplan J,Rozet JM,Gerard X
Wed Aug 01 00:00:00 EDT 2018
Super-Resolution Imaging Reveals TCTN2 Depletion-Induced IFT88 Lumen Leakage and Ciliary Weakening.
Biophysical journal
Weng RR,Yang TT,Huang CE,Chang CW,Wang WJ,Liao JC
Tue Jul 17 00:00:00 EDT 2018
Centrobin controls primary ciliogenesis in vertebrates.
The Journal of cell biology
Ogungbenro YA,Tena TC,Gaboriau D,Lalor P,Dockery P,Philipp M,Morrison CG
Mon Apr 02 00:00:00 EDT 2018
VPS4 is a dynamic component of the centrosome that regulates centrosome localization of γ-tubulin, centriolar satellite stability and ciliogenesis.
Scientific reports
Ott C,Nachmias D,Adar S,Jarnik M,Sherman S,Birnbaum RY,Lippincott-Schwartz J,Elia N
Tue Feb 20 00:00:00 EST 2018
Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.
American journal of human genetics
Bozal-Basterra L,Martín-Ruíz I,Pirone L,Liang Y,Sigurðsson JO,Gonzalez-Santamarta M,Giordano I,Gabicagogeascoa E,de Luca A,Rodríguez JA,Wilkie AOM,Kohlhase J,Eastwood D,Yale C,Olsen JV,Rauchman M,Anderson KV,Sutherland JD,Barrio R
Thu Feb 01 00:00:00 EST 2018
Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.
American journal of human genetics
Bozal-Basterra L,Martín-Ruíz I,Pirone L,Liang Y,Sigurðsson JO,Gonzalez-Santamarta M,Giordano I,Gabicagogeascoa E,de Luca A,Rodríguez JA,Wilkie AOM,Kohlhase J,Eastwood D,Yale C,Olsen JV,Rauchman M,Anderson KV,Sutherland JD,Barrio R
Thu Feb 01 00:00:00 EST 2018
Export of membrane proteins from the Golgi complex to the primary cilium requires the kinesin motor, KIFC1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Lee SH,Joo K,Jung EJ,Hong H,Seo J,Kim J
Thu Feb 01 00:00:00 EST 2018
The small GTPase RSG1 controls a final step in primary cilia initiation.
The Journal of cell biology
Agbu SO,Liang Y,Liu A,Anderson KV
Tue Jan 02 00:00:00 EST 2018
Centriole triplet microtubules are required for stable centriole formation and inheritance in human cells.
eLife
Wang JT,Kong D,Hoerner CR,Loncarek J,Stearns T
Thu Sep 14 00:00:00 EDT 2017
Asymmetric Centriole Numbers at Spindle Poles Cause Chromosome Missegregation in Cancer.
Cell reports
Cosenza MR,Cazzola A,Rossberg A,Schieber NL,Konotop G,Bausch E,Slynko A,Holland-Letz T,Raab MS,Dubash T,Glimm H,Poppelreuther S,Herold-Mende C,Schwab Y,Krämer A
Tue Aug 22 00:00:00 EDT 2017
Identification of Chlamydomonas Central Core Centriolar Proteins Reveals a Role for Human WDR90 in Ciliogenesis.
Current biology : CB
Hamel V,Steib E,Hamelin R,Armand F,Borgers S,Flückiger I,Busso C,Olieric N,Sorzano COS,Steinmetz MO,Guichard P,Gönczy P
Mon Aug 21 00:00:00 EDT 2017
Human microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles.
Nature communications
Chen HY,Wu CT,Tang CC,Lin YN,Wang WJ,Tang TK
Tue Aug 15 00:00:00 EDT 2017
The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome.
The Journal of cell biology
Loukil A,Tormanen K,Sütterlin C
Mon May 01 00:00:00 EDT 2017
The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome.
The Journal of cell biology
Loukil A,Tormanen K,Sütterlin C
Mon May 01 00:00:00 EDT 2017
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Nature communications
Li X,Song N,Liu L,Liu X,Ding X,Song X,Yang S,Shan L,Zhou X,Su D,Wang Y,Zhang Q,Cao C,Ma S,Yu N,Yang F,Wang Y,Yao Z,Shang Y,Shi L
Fri Mar 31 00:00:00 EDT 2017
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Nature communications
Li X,Song N,Liu L,Liu X,Ding X,Song X,Yang S,Shan L,Zhou X,Su D,Wang Y,Zhang Q,Cao C,Ma S,Yu N,Yang F,Wang Y,Yao Z,Shang Y,Shi L
Fri Mar 31 00:00:00 EDT 2017
Zika virus causes supernumerary foci with centriolar proteins and impaired spindle positioning.
Open biology
Wolf B,Diop F,Ferraris P,Wichit S,Busso C,Missé D,Gönczy P
Sun Jan 01 00:00:00 EST 2017
KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification.
Nature communications
Fournier M,Orpinell M,Grauffel C,Scheer E,Garnier JM,Ye T,Chavant V,Joint M,Esashi F,Dejaegere A,Gönczy P,Tora L
Mon Oct 31 00:00:00 EDT 2016
Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis.
eLife
Walentek P,Quigley IK,Sun DI,Sajjan UK,Kintner C,Harland RM
Tue Sep 13 00:00:00 EDT 2016
A Conserved Role for Girdin in Basal Body Positioning and Ciliogenesis.
Developmental cell
Nechipurenko IV,Olivier-Mason A,Kazatskaya A,Kennedy J,McLachlan IG,Heiman MG,Blacque OE,Sengupta P
Mon Sep 12 00:00:00 EDT 2016
Fidgetin-like 1 is a ciliogenesis-inhibitory centrosome protein.
Cell cycle (Georgetown, Tex.)
Zhao X,Jin M,Wang M,Sun L,Hong X,Cao Y,Wang C
Thu Sep 01 00:00:00 EDT 2016
Cep295 is a conserved scaffold protein required for generation of a bona fide mother centriole.
Nature communications
Tsuchiya Y,Yoshiba S,Gupta A,Watanabe K,Kitagawa D
Fri Aug 26 00:00:00 EDT 2016
CEP295 interacts with microtubules and is required for centriole elongation.
Journal of cell science
Chang CW,Hsu WB,Tsai JJ,Tang CJ,Tang TK
Fri Jul 01 00:00:00 EDT 2016
MCRS1 associates with cytoplasmic dynein and mediates pericentrosomal material recruitment.
Scientific reports
Lee SH,Lee MS,Choi TI,Hong H,Seo JY,Kim CH,Kim J
Mon Jun 06 00:00:00 EDT 2016
Centrosomal protein CP110 controls maturation of the mother centriole during cilia biogenesis.
Development (Cambridge, England)
Yadav SP,Sharma NK,Liu C,Dong L,Li T,Swaroop A
Sun May 01 00:00:00 EDT 2016
Mutations in human C2CD3 cause skeletal dysplasia and provide new insights into phenotypic and cellular consequences of altered C2CD3 function.
Scientific reports
Cortés CR,McInerney-Leo AM,Vogel I,Rondón Galeano MC,Leo PJ,Harris JE,Anderson LK,Keith PA,Brown MA,Ramsing M,Duncan EL,Zankl A,Wicking C
Wed Apr 20 00:00:00 EDT 2016
SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.
Nature cell biology
Hilbert M,Noga A,Frey D,Hamel V,Guichard P,Kraatz SH,Pfreundschuh M,Hosner S,Flückiger I,Jaussi R,Wieser MM,Thieltges KM,Deupi X,Müller DJ,Kammerer RA,Gönczy P,Hirono M,Steinmetz MO
Fri Apr 01 00:00:00 EDT 2016
The Tumor Suppressor Cdkn3 Is Required for Maintaining the Proper Number of Centrosomes by Regulating the Centrosomal Stability of Mps1.
Cell reports
Srinivas V,Kitagawa M,Wong J,Liao PJ,Lee SH
Tue Nov 24 00:00:00 EST 2015
Specific CP110 Phosphorylation Sites Mediate Anaphase Catastrophe after CDK2 Inhibition: Evidence for Cooperation with USP33 Knockdown.
Molecular cancer therapeutics
Hu S,Lu Y,Orr B,Godek K,Mustachio LM,Kawakami M,Sekula D,Compton DA,Freemantle S,Dmitrovsky E
Sun Nov 01 00:00:00 EDT 2015
MiR-129-3p promotes docetaxel resistance of breast cancer cells via CP110 inhibition.
Scientific reports
Zhang Y,Wang Y,Wei Y,Li M,Yu S,Ye M,Zhang H,Chen S,Liu W,Zhang J
Wed Oct 21 00:00:00 EDT 2015
MiR-129-3p promotes docetaxel resistance of breast cancer cells via CP110 inhibition.
Scientific reports
Zhang Y,Wang Y,Wei Y,Li M,Yu S,Ye M,Zhang H,Chen S,Liu W,Zhang J
Wed Oct 21 00:00:00 EDT 2015
Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication.
eLife
Kodani A,Yu TW,Johnson JR,Jayaraman D,Johnson TL,Al-Gazali L,Sztriha L,Partlow JN,Kim H,Krup AL,Dammermann A,Krogan NJ,Walsh CA,Reiter JF
Sat Aug 22 00:00:00 EDT 2015
Deacetylation of α-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly.
Scientific reports
Ran J,Yang Y,Li D,Liu M,Zhou J
Thu Aug 06 00:00:00 EDT 2015
Myosin heavy chain 10 (MYH10) is required for centriole migration during the biogenesis of primary cilia.
Biochemical and biophysical research communications
Hong H,Kim J,Kim J
Fri May 22 00:00:00 EDT 2015
Centrin2 regulates CP110 removal in primary cilium formation.
The Journal of cell biology
Prosser SL,Morrison CG
Mon Mar 16 00:00:00 EDT 2015
Centrin2 regulates CP110 removal in primary cilium formation.
The Journal of cell biology
Prosser SL,Morrison CG
Mon Mar 16 00:00:00 EDT 2015
The Microtubule-Depolymerizing Activity of a Mitotic Kinesin Protein KIF2A Drives Primary Cilia Disassembly Coupled with Cell Proliferation.
Cell reports
Miyamoto T,Hosoba K,Ochiai H,Royba E,Izumi H,Sakuma T,Yamamoto T,Dynlacht BD,Matsuura S
Tue Feb 10 00:00:00 EST 2015
Lineage specificity of primary cilia in the mouse embryo.
Nature cell biology
Bangs FK,Schrode N,Hadjantonakis AK,Anderson KV
Sun Feb 01 00:00:00 EST 2015
Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing.
Nature cell biology
Pagan JK,Marzio A,Jones MJ,Saraf A,Jallepalli PV,Florens L,Washburn MP,Pagano M
Thu Jan 01 00:00:00 EST 2015
The MST1/2-SAV1 complex of the Hippo pathway promotes ciliogenesis.
Nature communications
Kim M,Kim M,Lee MS,Kim CH,Lim DS
Tue Nov 04 00:00:00 EST 2014
CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6.
Cell research
Yang Y,Ran J,Liu M,Li D,Li Y,Shi X,Meng D,Pan J,Ou G,Aneja R,Sun SC,Zhou J
Sat Nov 01 00:00:00 EDT 2014
CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6.
Cell research
Yang Y,Ran J,Liu M,Li D,Li Y,Shi X,Meng D,Pan J,Ou G,Aneja R,Sun SC,Zhou J
Sat Nov 01 00:00:00 EDT 2014
Stabilization of cartwheel-less centrioles for duplication requires CEP295-mediated centriole-to-centrosome conversion.
Cell reports
Izquierdo D,Wang WJ,Uryu K,Tsou MF
Thu Aug 21 00:00:00 EDT 2014
SAS-6 assembly templated by the lumen of cartwheel-less centrioles precedes centriole duplication.
Developmental cell
Fong CS,Kim M,Yang TT,Liao JC,Tsou MF
Mon Jul 28 00:00:00 EDT 2014
PIPKIγ targets to the centrosome and restrains centriole duplication.
Journal of cell science
Xu Q,Zhang Y,Xiong X,Huang Y,Salisbury JL,Hu J,Ling K
Sat Mar 15 00:00:00 EDT 2014
Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells.
The Journal of cell biology
Keller D,Orpinell M,Olivier N,Wachsmuth M,Mahen R,Wyss R,Hachet V,Ellenberg J,Manley S,Gönczy P
Mon Mar 03 00:00:00 EST 2014
C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.
Proceedings of the National Academy of Sciences of the United States of America
Ye X,Zeng H,Ning G,Reiter JF,Liu A
Tue Feb 11 00:00:00 EST 2014
The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis.
Nature cell biology
Zhao H,Zhu L,Zhu Y,Cao J,Li S,Huang Q,Xu T,Huang X,Yan X,Zhu X
Sun Dec 01 00:00:00 EST 2013
CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base.
Nature cell biology
Wang WJ,Tay HG,Soni R,Perumal GS,Goll MG,Macaluso FP,Asara JM,Amack JD,Tsou MF
Sat Jun 01 00:00:00 EDT 2013
CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base.
Nature cell biology
Wang WJ,Tay HG,Soni R,Perumal GS,Goll MG,Macaluso FP,Asara JM,Amack JD,Tsou MF
Sat Jun 01 00:00:00 EDT 2013
CCDC41 is required for ciliary vesicle docking to the mother centriole.
Proceedings of the National Academy of Sciences of the United States of America
Joo K,Kim CG,Lee MS,Moon HY,Lee SH,Kim MJ,Kweon HS,Park WY,Kim CH,Gleeson JG,Kim J
Tue Apr 09 00:00:00 EDT 2013
USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110.
Nature
Li J,D'Angiolella V,Seeley ES,Kim S,Kobayashi T,Fu W,Campos EI,Pagano M,Dynlacht BD
Thu Mar 14 00:00:00 EDT 2013
Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages.
The EMBO journal
Kodani A,Salomé Sirerol-Piquer M,Seol A,Garcia-Verdugo JM,Reiter JF
Wed Feb 20 00:00:00 EST 2013
miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics.
Nature cell biology
Cao J,Shen Y,Zhu L,Xu Y,Zhou Y,Wu Z,Li Y,Yan X,Zhu X
Sun Jun 10 00:00:00 EDT 2012
miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics.
Nature cell biology
Cao J,Shen Y,Zhu L,Xu Y,Zhou Y,Wu Z,Li Y,Yan X,Zhu X
Sun Jun 10 00:00:00 EDT 2012
